Title |
Charakterisierung des EGF-Rezeptorstatus beim Peniskarzinom
|
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Published in |
Die Urologie, September 2009
|
DOI | 10.1007/s00120-009-2101-6 |
Pubmed ID | |
Authors |
C. Börgermann, K.J. Schmitz, S. Sommer, H. Rübben, S. Krege |
Abstract |
Therapeutic success in metastasized squamous cell carcinoma is poor. Some entities, such as head-and-neck tumors or non-small-cell lung cancer, show an over expression of the EGF receptor. In latest studies target-specific substances against the EGF receptor have already been combined with chemotherapy or radiotherapy. Some studies showed a clear advantage of this combination concerning remission rates as well as survival. EGF receptor status has not yet been examined in penile cancer, therefore, a retrospective analysis of the receptor status was performed in patients treated over the last 14 years and correlations with the clinical course were investigated. |