| Title |
Physical activity and change in fasting glucose and HbA1c: a quantitative meta-analysis of randomized trials
|
|---|---|
| Published in |
Acta Diabetologica, August 2017
|
| DOI | 10.1007/s00592-017-1037-3 |
| Pubmed ID | |
| Authors |
Mathieu Boniol, Miruna Dragomir, Philippe Autier, Peter Boyle |
| Abstract |
A systematic review was conducted of randomized trials which evaluated the impact of physical activity on the change in fasting glucose and HbA1c. A literature search was conducted in PubMed until December 2015. Studies reporting glucose or HbA1c at baseline and at the end of study were included, and the change and its variance were estimated from studies with complete data. Mixed-effect random models were used to estimate the change of fasting glucose (mg/dl) and HbA1c (%) per additional minutes of physical activity per week. A total of 125 studies were included in the meta-analysis. Based on 105 studies, an increase of 100 min in physical activity per week was associated with an average change of -2.75 mg/dl of fasting glucose (95% CI -3.96; -1.55), although there was a high degree of heterogeneity (83.5%). When restricting the analysis on type 2 diabetes and prediabetes subjects (56 studies), the average change in fasting glucose was -4.71 mg/dl (95% CI -7.42; -2.01). For HbA1c, among 76 studies included, an increase of 100 min in physical activity per week was associated with an average change of -0.14% of HbA1c (95% CI -0.18; -0.09) with heterogeneity (73%). A large degree of publication bias was identified (Egger test p < 0.001). When restricting the analysis on type 2 diabetes and prediabetes subjects (60 studies), the average change in HbA1c was -0.16% (95% CI -0.21; -0.11). This analysis demonstrates that moderate increases in physical activity are associated with significant reductions in both fasting glucose and HbA1c. |
Mendeley readers
The data shown below were compiled from readership statistics for 187 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 187 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 22 | 12% |
| Researcher | 21 | 11% |
| Student > Ph. D. Student | 21 | 11% |
| Student > Bachelor | 21 | 11% |
| Other | 8 | 4% |
| Other | 30 | 16% |
| Unknown | 64 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 48 | 26% |
| Nursing and Health Professions | 32 | 17% |
| Biochemistry, Genetics and Molecular Biology | 11 | 6% |
| Sports and Recreations | 8 | 4% |
| Agricultural and Biological Sciences | 6 | 3% |
| Other | 13 | 7% |
| Unknown | 69 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 January 2020.
All research outputs
#20,444,703
of 22,999,744 outputs
Outputs from Acta Diabetologica
#761
of 928 outputs
Outputs of similar age
#277,058
of 317,238 outputs
Outputs of similar age from Acta Diabetologica
#6
of 9 outputs
Altmetric has tracked 22,999,744 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 928 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 317,238 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.