Title |
The Economic Burden of Treatment-Resistant Depression
|
---|---|
Published in |
Clinical Therapeutics, March 2013
|
DOI | 10.1016/j.clinthera.2012.09.001 |
Pubmed ID | |
Authors |
Natalia Olchanski, Michelle McInnis Myers, Marilyn Halseth, Philip L. Cyr, Lindsay Bockstedt, Thomas F. Goss, Robert H. Howland |
Abstract |
Major depressive disorder (MDD) is a leading cause of disability, morbidity, and mortality worldwide. The lifetime prevalence in the United States is estimated at 17%. Treatment-resistant depression (TRD) is generally defined as failure to achieve remissions despite adequate treatment. About 30% of patients do not achieve remission after 4 different antidepressant treatment trials. A few studies have examined the economic burden of TRD, but none has investigated the cost associated with more chronic and extensive forms of TRD characterized by nonresponse to ≥4 treatment trials. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Netherlands | 1 | <1% |
Canada | 1 | <1% |
Brazil | 1 | <1% |
Unknown | 173 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 29 | 16% |
Student > Master | 15 | 8% |
Student > Doctoral Student | 15 | 8% |
Researcher | 14 | 8% |
Other | 13 | 7% |
Other | 32 | 18% |
Unknown | 59 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 35 | 20% |
Psychology | 18 | 10% |
Neuroscience | 17 | 10% |
Biochemistry, Genetics and Molecular Biology | 9 | 5% |
Social Sciences | 7 | 4% |
Other | 27 | 15% |
Unknown | 64 | 36% |