Title |
Cutaneous vasculitis associated with fluoroquinolones
|
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Published in |
Infection, August 2009
|
DOI | 10.1007/s15010-009-8437-4 |
Pubmed ID | |
Authors |
G. Maunz, T. Conzett, W. Zimmerli |
Abstract |
Cutaneous vasculitis is a clinical entity with a broad differential diagnosis, including an adverse drug reaction. It is defined as inflammation of skin blood vessel walls. During a 7-year-period, we observed three patients who developed isolated cutaneous vasculitis during antibiotic therapy of bacterial infection. All were treated with a fluoroquinolone (ciprofloxacin or levofloxacin) combined with rifampin (two cases) or flucloxacillin (three cases), respectively. In all three cases the lesions gradually resolved after treatment with the inciting fluoroquinolone had been stopped. In one patient, leukocytoclastic small-vessel vasculitis was histologically confirmed. Fluoroquinolone-associated cutaneous vasculitis consists of an isolated self-limiting disorder that is part of a systemic vasculitis, or even life-threatening disease. Clinicians should be aware of this serious adverse event because any continuation of treatment may be fatal. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 14 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 5 | 36% |
Other | 2 | 14% |
Student > Doctoral Student | 2 | 14% |
Student > Master | 2 | 14% |
Unspecified | 1 | 7% |
Other | 1 | 7% |
Unknown | 1 | 7% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 4 | 29% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
Biochemistry, Genetics and Molecular Biology | 1 | 7% |
Unspecified | 1 | 7% |
Business, Management and Accounting | 1 | 7% |
Other | 3 | 21% |
Unknown | 3 | 21% |