Title |
Effects of Excessive Dietary Phosphorus Intake on Bone Health
|
---|---|
Published in |
Current Osteoporosis Reports, August 2017
|
DOI | 10.1007/s11914-017-0398-4 |
Pubmed ID | |
Authors |
Colby J. Vorland, Elizabeth R. Stremke, Ranjani N. Moorthi, Kathleen M. Hill Gallant |
Abstract |
The purpose of this review is to provide an overview of dietary phosphorus, its sources, recommended intakes, and its absorption and metabolism in health and in chronic kidney disease and to discuss recent findings in this area with a focus on the effects of inorganic phosphate additives in bone health. Recent findings show that increasing dietary phosphorus through inorganic phosphate additives has detrimental effects on bone and mineral metabolism in humans and animals. There is new data supporting an educational intervention to limit phosphate additives in patients with chronic kidney disease to control serum phosphate. The average intake of phosphorus in the USA is well above the recommended dietary allowance. Inorganic phosphate additives, which are absorbed at a high rate, account for a substantial and likely underestimated portion of this excessive intake. These additives have negative effects on bone metabolism and present a prime opportunity to lower total phosphorus intake in the USA. Further evidence is needed to confirm whether lowering dietary phosphorus intake would have beneficial effects to improve fracture risk. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 21 | 41% |
United States | 2 | 4% |
Colombia | 1 | 2% |
Ecuador | 1 | 2% |
Netherlands | 1 | 2% |
Mexico | 1 | 2% |
Venezuela, Bolivarian Republic of | 1 | 2% |
Unknown | 23 | 45% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 41 | 80% |
Practitioners (doctors, other healthcare professionals) | 7 | 14% |
Scientists | 3 | 6% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 179 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 30 | 17% |
Student > Master | 22 | 12% |
Researcher | 14 | 8% |
Other | 11 | 6% |
Student > Ph. D. Student | 11 | 6% |
Other | 28 | 16% |
Unknown | 63 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 26 | 15% |
Nursing and Health Professions | 20 | 11% |
Biochemistry, Genetics and Molecular Biology | 14 | 8% |
Agricultural and Biological Sciences | 14 | 8% |
Engineering | 6 | 3% |
Other | 28 | 16% |
Unknown | 71 | 40% |