↓ Skip to main content

Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets

Overview of attention for article published in BMC Medicine, June 2014
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

news
2 news outlets
blogs
1 blog
twitter
8 X users

Citations

dimensions_citation
122 Dimensions

Readers on

mendeley
171 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets
Published in
BMC Medicine, June 2014
DOI 10.1186/1741-7015-12-103
Pubmed ID
Authors

Elin Hall, Petr Volkov, Tasnim Dayeh, Karl Bacos, Tina Rönn, Marloes Dekker Nitert, Charlotte Ling

Abstract

Circulating free fatty acids are often elevated in patients with type 2 diabetes (T2D) and obese individuals. Chronic exposure to high levels of saturated fatty acids has detrimental effects on islet function and insulin secretion. Altered gene expression and epigenetics may contribute to T2D and obesity. However, there is limited information on whether fatty acids alter the genome-wide transcriptome profile in conjunction with DNA methylation patterns in human pancreatic islets. To dissect the molecular mechanisms linking lipotoxicity to impaired insulin secretion, we investigated the effects of a 48 h palmitate treatment in vitro on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 171 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Sweden 1 <1%
Unknown 168 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 35 20%
Researcher 29 17%
Student > Master 20 12%
Student > Bachelor 20 12%
Student > Doctoral Student 13 8%
Other 23 13%
Unknown 31 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 45 26%
Agricultural and Biological Sciences 42 25%
Medicine and Dentistry 29 17%
Nursing and Health Professions 6 4%
Pharmacology, Toxicology and Pharmaceutical Science 3 2%
Other 12 7%
Unknown 34 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 27. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 July 2015.
All research outputs
#1,436,178
of 25,331,507 outputs
Outputs from BMC Medicine
#1,015
of 3,987 outputs
Outputs of similar age
#13,907
of 235,102 outputs
Outputs of similar age from BMC Medicine
#17
of 56 outputs
Altmetric has tracked 25,331,507 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,987 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.5. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,102 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.