| Title |
Vitamin D3 affects innate immune status of European sea bass (Dicentrarchus labrax L.)
|
|---|---|
| Published in |
Fish Physiology and Biochemistry, April 2017
|
| DOI | 10.1007/s10695-017-0362-3 |
| Pubmed ID | |
| Authors |
M. Dioguardi, F. A. Guardiola, M. Vazzana, A. Cuesta, M. A. Esteban, M. Cammarata |
| Abstract |
The effects of vitamin D3 dietary administration on certain innate immune parameters on the expression of immune-related genes in head-kidney (HK) and gut were investigated in European sea bass Dicentrarchus labrax. Vitamin D3 (vD3) was orally administered to fish in a commercial pellet food supplemented with 0 (control); 3750; 18,750; or 37,500 U kg(-1). Furthermore, gut histology was considered. This study showed a modulation in the activities examined in fish fed with the addition of vD3. After just 2 weeks of administration, diet supplementation with the vitamin resulted in increased phagocytic ability, while serum peroxidase content was increased in fish fed with all experimental diets after 4 weeks, no significant differences were observed in protease, anti-protease, natural haemolytic complement activities and total IgM level. At gene level, fbl and rbl transcripts were up-regulated in HK in fish fed with the highest concentration of vD3-supplemented diets after 4 weeks, while in the gut, an up-regulation of hep gene was observed in fish fed with the different doses of vD3. These results suggest that vD3 may be of great interest for immunostimulatory purposes in fish farms. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 47 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 8 | 17% |
| Student > Master | 8 | 17% |
| Student > Ph. D. Student | 5 | 11% |
| Student > Postgraduate | 3 | 6% |
| Student > Bachelor | 3 | 6% |
| Other | 9 | 19% |
| Unknown | 11 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 21 | 45% |
| Medicine and Dentistry | 5 | 11% |
| Biochemistry, Genetics and Molecular Biology | 3 | 6% |
| Veterinary Science and Veterinary Medicine | 2 | 4% |
| Unspecified | 1 | 2% |
| Other | 2 | 4% |
| Unknown | 13 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 September 2017.
All research outputs
#18,569,430
of 22,999,744 outputs
Outputs from Fish Physiology and Biochemistry
#414
of 867 outputs
Outputs of similar age
#235,013
of 308,974 outputs
Outputs of similar age from Fish Physiology and Biochemistry
#4
of 10 outputs
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