Title |
Beyond chemotherapy and targeted therapy: adoptive cellular therapy in non-small cell lung cancer
|
---|---|
Published in |
Molecular Biology Reports, June 2014
|
DOI | 10.1007/s11033-014-3514-x |
Pubmed ID | |
Authors |
Junying Wang, Xueju Wang |
Abstract |
Non-small cell lung cancer (NSCLC) is an intractable disease for which effective treatment approaches are urgently needed. The ability to induce antigen-specific immune responses in patients with lung cancer has led to the development of immunotherapy as a novel concept for the treatment of NSCLC. Adoptive cellular therapy (ACT) represents an important advancement in cancer immunotherapy with the utilization of tumor infiltrating lymphocytes, cytokine-induced killer cells, natural killer cells and γδ T cells. In this study, we review recent advances in ACT for NSCLC in clinical trials and provide a perspective on the improvement in ACT and potential therapeutic approaches using engineered T cell therapy for NSCLC. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 5 | 20% |
Student > Postgraduate | 5 | 20% |
Other | 3 | 12% |
Student > Bachelor | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Other | 2 | 8% |
Unknown | 5 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 40% |
Biochemistry, Genetics and Molecular Biology | 4 | 16% |
Agricultural and Biological Sciences | 2 | 8% |
Philosophy | 1 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 4% |
Other | 2 | 8% |
Unknown | 5 | 20% |