Title |
Rapid exacerbation of renal function after administration of hydroxyethyl starch in a dog
|
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Published in |
Journal of Veterinary Medical Science, September 2017
|
DOI | 10.1292/jvms.17-0196 |
Pubmed ID | |
Authors |
Junwoo Bae, Mahmoud Soliman, Hyunwoo Kim, Seongwoo Kang, Woosun Kim, Soomin Ahn, Kyoungoh Cho, Jihye Choi, Suhee Kim, Jinho Park, Sangki Kim, Yoonjung DO, Jaegyu Yoo, Dohyeon Yu |
Abstract |
Hydroxyethyl starches (HES) are commonly used synthetic colloidal solution in veterinary medicine. Despite of possible adverse effect to kidney injury in human, there is no report about nephrotoxic effects of HES in dogs. HES was administered to a Golden retriever (4-year-old, intact male) with ascites in order to increase plasma osmolality. Initially, the dog was mild azotemic, however, kidney function was rapidly deteriorated after several days of HES administration. Finally, histopathological examination revealed remarkable osmotic nephrosis. In the case reported herein, acute kidney injury was remarkably developed after HES administration. Clinical and histopathologic findings of acute kidney injury support nephrotoxic effects of HES to a dog. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 1 | 17% |
Spain | 1 | 17% |
Japan | 1 | 17% |
Unknown | 3 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 17 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 3 | 18% |
Student > Bachelor | 3 | 18% |
Student > Master | 2 | 12% |
Student > Postgraduate | 2 | 12% |
Professor | 1 | 6% |
Other | 2 | 12% |
Unknown | 4 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 7 | 41% |
Agricultural and Biological Sciences | 3 | 18% |
Medicine and Dentistry | 2 | 12% |
Nursing and Health Professions | 1 | 6% |
Unknown | 4 | 24% |