| Title |
Salivary Biomarkers for Detection of Oral Squamous Cell Carcinoma: Current State and Recent Advances
|
|---|---|
| Published in |
Current Oral Health Reports, March 2014
|
| DOI | 10.1007/s40496-014-0014-y |
| Pubmed ID | |
| Authors |
Maha Yakob, Laurel Fuentes, Marilene B. Wang, Elliot Abemayor, David T.W. Wong |
| Abstract |
Oral squamous cell carcinoma (OSCC) is the most common malignant neoplasm of the oral cavity. Detection of OSCC is currently based on thorough clinical oral examination combined with biopsy for histological analysis. Most cases of OSCC are not detected until the cancer has developed into advanced stages; thus, a reliable early stage diagnostic marker is needed. This literature review presents an overview of the status of current advances in salivary diagnostics for OSCC. Though many protein and mRNA salivary biomarkers have been identified that can detect OSCC with high sensitivity and specificity, the most discernable findings occur with the use of multiple markers. Studies that incorporate proteomic, transcriptomic, and potentially additional "omics", including methylomics, need to be initiated to bring technology to clinical applications and allow the best use of saliva in diagnosing OSCC. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 174 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 27 | 15% |
| Student > Ph. D. Student | 26 | 15% |
| Student > Bachelor | 22 | 13% |
| Researcher | 19 | 11% |
| Student > Postgraduate | 13 | 7% |
| Other | 28 | 16% |
| Unknown | 40 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 56 | 32% |
| Biochemistry, Genetics and Molecular Biology | 33 | 19% |
| Agricultural and Biological Sciences | 12 | 7% |
| Engineering | 8 | 5% |
| Physics and Astronomy | 4 | 2% |
| Other | 14 | 8% |
| Unknown | 48 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 July 2020.
All research outputs
#6,940,930
of 22,758,248 outputs
Outputs from Current Oral Health Reports
#18
of 78 outputs
Outputs of similar age
#66,728
of 223,408 outputs
Outputs of similar age from Current Oral Health Reports
#1
of 4 outputs
Altmetric has tracked 22,758,248 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 78 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
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We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them