| Title |
Memory deficits in amyotrophic lateral sclerosis are not exclusively caused by executive dysfunction: a comparative neuropsychological study of amnestic mild cognitive impairment
|
|---|---|
| Published in |
BMC Neuroscience, June 2014
|
| DOI | 10.1186/1471-2202-15-83 |
| Pubmed ID | |
| Authors |
Judith Machts, Verena Bittner, Elisabeth Kasper, Christina Schuster, Johannes Prudlo, Susanne Abdulla, Katja Kollewe, Susanne Petri, Reinhard Dengler, Hans-Jochen Heinze, Stefan Vielhaber, Mircea A Schoenfeld, Daniel M Bittner |
| Abstract |
Recent work suggests that ALS and frontotemporal dementia can occur together and share at least in part the same underlying pathophysiology. However, it is unclear at present whether memory deficits in ALS stem from a temporal lobe dysfunction, or are rather driven by frontal executive dysfunction. In this study we sought to investigate the nature of memory deficits by analyzing the neuropsychological performance of 40 ALS patients in comparison to 39 amnestic mild cognitive impairment (aMCI) patients and 40 healthy controls (HC). The neuropsychological battery tested for executive functions, as well as memory and visuo-spatial skills, the results of which were compared across study groups. In addition, we calculated composite scores for memory (learning, recall, recognition) and executive functions (verbal fluency, cognitive flexibility, working memory). We hypothesized that the nature of memory impairment in ALS will be different from those exhibited by aMCI patients. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | <1% |
| Unknown | 101 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 16% |
| Student > Master | 15 | 15% |
| Student > Bachelor | 15 | 15% |
| Researcher | 13 | 13% |
| Student > Doctoral Student | 7 | 7% |
| Other | 13 | 13% |
| Unknown | 23 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 28 | 27% |
| Neuroscience | 18 | 18% |
| Medicine and Dentistry | 13 | 13% |
| Biochemistry, Genetics and Molecular Biology | 5 | 5% |
| Agricultural and Biological Sciences | 4 | 4% |
| Other | 9 | 9% |
| Unknown | 25 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 September 2021.
All research outputs
#17,723,043
of 22,758,248 outputs
Outputs from BMC Neuroscience
#812
of 1,242 outputs
Outputs of similar age
#154,451
of 226,817 outputs
Outputs of similar age from BMC Neuroscience
#24
of 35 outputs
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We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.