| Title |
Homogeneous Subgroups of Young Children with Autism Improve Phenotypic Characterization in the Study to Explore Early Development
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, September 2017
|
| DOI | 10.1007/s10803-017-3280-4 |
| Pubmed ID | |
| Authors |
Lisa D. Wiggins, Lin H. Tian, Susan E. Levy, Catherine Rice, Li-Ching Lee, Laura Schieve, Juhi Pandey, Julie Daniels, Lisa Blaskey, Susan Hepburn, Rebecca Landa, Rebecca Edmondson-Pretzel, William Thompson |
| Abstract |
The objective of this study was to identify homogenous classes of young children with autism spectrum disorder (ASD) to improve phenotypic characterization. Children were enrolled in the Study to Explore Early Development between 2 and 5 years of age. 707 children were classified with ASD after a comprehensive evaluation with strict diagnostic algorithms. Four classes of children with ASD were identified from latent class analysis: mild language delay with cognitive rigidity, mild language and motor delay with dysregulation, general developmental delay, and significant developmental delay with repetitive motor behaviors. We conclude that a four-class phenotypic model of children with ASD best describes our data and improves phenotypic characterization of young children with ASD. Implications for screening, diagnosis, and research are discussed. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 103 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 103 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 16 | 16% |
| Student > Ph. D. Student | 14 | 14% |
| Student > Doctoral Student | 11 | 11% |
| Researcher | 9 | 9% |
| Other | 8 | 8% |
| Other | 15 | 15% |
| Unknown | 30 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 34 | 33% |
| Social Sciences | 10 | 10% |
| Neuroscience | 8 | 8% |
| Medicine and Dentistry | 5 | 5% |
| Nursing and Health Professions | 3 | 3% |
| Other | 10 | 10% |
| Unknown | 33 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2018.
All research outputs
#7,301,919
of 25,654,806 outputs
Outputs from Journal of Autism and Developmental Disorders
#2,572
of 5,484 outputs
Outputs of similar age
#105,419
of 324,015 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#53
of 96 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 5,484 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,015 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.