| Title |
Exploring the therapeutic role of creatine supplementation
|
|---|---|
| Published in |
Amino Acids, March 2009
|
| DOI | 10.1007/s00726-009-0263-6 |
| Pubmed ID | |
| Authors |
Bruno Gualano, Guilherme Giannini Artioli, Jacques R. Poortmans, Antonio Herbert Lancha Junior |
| Abstract |
Creatine (Cr) plays a central role in energy provision through a reaction catalyzed by phosphorylcreatine kinase. Furthermore, this amine enhances both gene expression and satellite cell activation involved in hypertrophic response. Recent findings have indicated that Cr supplementation has a therapeutic role in several diseases characterized by atrophic conditions, weakness, and metabolic disturbances (i.e., in the muscle, bone, lung, and brain). Accordingly, there has been an evidence indicating that Cr supplementation is capable of attenuating the degenerative state in some muscle disorders (i.e., Duchenne and inflammatory myopathies), central nervous diseases (i.e., Parkinson's, Huntington's, and Alzheimer's), and bone and metabolic disturbances (i.e., osteoporosis and type II diabetes). In light of this, Cr supplementation could be used as a therapeutic tool for the elderly. The aim of this review is to summarize the main studies conducted in this field and to highlight the scientific and clinical perspectives of this promising therapeutic supplement. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | 50% |
| United States | 1 | 25% |
| United Kingdom | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 2 | 50% |
| Scientists | 1 | 25% |
| Members of the public | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 221 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 5 | 2% |
| United Kingdom | 3 | 1% |
| United States | 2 | <1% |
| Australia | 1 | <1% |
| Germany | 1 | <1% |
| Netherlands | 1 | <1% |
| Switzerland | 1 | <1% |
| Unknown | 207 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 37 | 17% |
| Researcher | 27 | 12% |
| Student > Ph. D. Student | 26 | 12% |
| Student > Master | 25 | 11% |
| Other | 17 | 8% |
| Other | 38 | 17% |
| Unknown | 51 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 48 | 22% |
| Sports and Recreations | 30 | 14% |
| Agricultural and Biological Sciences | 25 | 11% |
| Nursing and Health Professions | 14 | 6% |
| Neuroscience | 13 | 6% |
| Other | 34 | 15% |
| Unknown | 57 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 54. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2024.
All research outputs
#773,465
of 25,169,746 outputs
Outputs from Amino Acids
#33
of 1,617 outputs
Outputs of similar age
#1,718
of 104,610 outputs
Outputs of similar age from Amino Acids
#1
of 14 outputs
Altmetric has tracked 25,169,746 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,617 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,610 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.