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Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes

Overview of attention for article published in Diabetes, September 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • High Attention Score compared to outputs of the same age and source (91st percentile)

Mentioned by

blogs
1 blog
twitter
3 X users
wikipedia
8 Wikipedia pages
googleplus
1 Google+ user

Citations

dimensions_citation
330 Dimensions

Readers on

mendeley
461 Mendeley
citeulike
4 CiteULike
connotea
1 Connotea
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Title
Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
Published in
Diabetes, September 2011
DOI 10.2337/db11-0415
Pubmed ID
Authors

Rona J. Strawbridge, Josée Dupuis, Inga Prokopenko, Adam Barker, Emma Ahlqvist, Denis Rybin, John R. Petrie, Mary E. Travers, Nabila Bouatia-Naji, Antigone S. Dimas, Alexandra Nica, Eleanor Wheeler, Han Chen, Benjamin F. Voight, Jalal Taneera, Stavroula Kanoni, John F. Peden, Fabiola Turrini, Stefan Gustafsson, Carina Zabena, Peter Almgren, David J.P. Barker, Daniel Barnes, Elaine M. Dennison, Johan G. Eriksson, Per Eriksson, Elodie Eury, Lasse Folkersen, Caroline S. Fox, Timothy M. Frayling, Anuj Goel, Harvest F. Gu, Momoko Horikoshi, Bo Isomaa, Anne U. Jackson, Karen A. Jameson, Eero Kajantie, Julie Kerr-Conte, Teemu Kuulasmaa, Johanna Kuusisto, Ruth J.F. Loos, Jian'an Luan, Konstantinos Makrilakis, Alisa K. Manning, María Teresa Martínez-Larrad, Narisu Narisu, Maria Nastase Mannila, John Öhrvik, Clive Osmond, Laura Pascoe, Felicity Payne, Avan A. Sayer, Bengt Sennblad, Angela Silveira, Alena Stančáková, Kathy Stirrups, Amy J. Swift, Ann-Christine Syvänen, Tiinamaija Tuomi, Ferdinand M. van 't Hooft, Mark Walker, Michael N. Weedon, Weijia Xie, Björn Zethelius, Halit Ongen, Anders Mälarstig, Jemma C. Hopewell, Danish Saleheen, John Chambers, Sarah Parish, John Danesh, Jaspal Kooner, Claes-Göran Östenson, Lars Lind, Cyrus C. Cooper, Manuel Serrano-Ríos, Ele Ferrannini, Tom J. Forsen, Robert Clarke, Maria Grazia Franzosi, Udo Seedorf, Hugh Watkins, Philippe Froguel, Paul Johnson, Panos Deloukas, Francis S. Collins, Markku Laakso, Emmanouil T. Dermitzakis, Michael Boehnke, Mark I. McCarthy, Nicholas J. Wareham, Leif Groop, François Pattou, Anna L. Gloyn, George V. Dedoussis, Valeriya Lyssenko, James B. Meigs, Inês Barroso, Richard M. Watanabe, Erik Ingelsson, Claudia Langenberg, Anders Hamsten, Jose C. Florez

Abstract

Proinsulin is a precursor of mature insulin and C-peptide. Higher circulating proinsulin levels are associated with impaired β-cell function, raised glucose levels, insulin resistance, and type 2 diabetes (T2D). Studies of the insulin processing pathway could provide new insights about T2D pathophysiology.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 461 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 1%
United Kingdom 3 <1%
Germany 2 <1%
Switzerland 1 <1%
India 1 <1%
France 1 <1%
Netherlands 1 <1%
Nigeria 1 <1%
Iceland 1 <1%
Other 2 <1%
Unknown 442 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 94 20%
Student > Ph. D. Student 73 16%
Professor 60 13%
Student > Master 31 7%
Other 28 6%
Other 102 22%
Unknown 73 16%
Readers by discipline Count As %
Medicine and Dentistry 119 26%
Biochemistry, Genetics and Molecular Biology 95 21%
Agricultural and Biological Sciences 90 20%
Computer Science 8 2%
Nursing and Health Professions 8 2%
Other 47 10%
Unknown 94 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2022.
All research outputs
#2,199,655
of 26,017,215 outputs
Outputs from Diabetes
#929
of 10,004 outputs
Outputs of similar age
#9,941
of 133,756 outputs
Outputs of similar age from Diabetes
#6
of 71 outputs
Altmetric has tracked 26,017,215 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,004 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 133,756 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 71 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.