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Mechanisms Underlying the Effect of Acupuncture on Cognitive Improvement: A Systematic Review of Animal Studies

Overview of attention for article published in Journal of Neuroimmune Pharmacology, June 2014
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Title
Mechanisms Underlying the Effect of Acupuncture on Cognitive Improvement: A Systematic Review of Animal Studies
Published in
Journal of Neuroimmune Pharmacology, June 2014
DOI 10.1007/s11481-014-9550-4
Pubmed ID
Authors

Mason Chin Pang Leung, Ka Keung Yip, Yuen Shan Ho, Flora Ka Wai Siu, Wai Chin Li, Belinda Garner

Abstract

Acupuncture has been reported to be beneficial in treating cognitive impairment in various pathological conditions. This review describes the effort to understand the signaling pathways that underlie the acupunctural therapeutic effect on cognitive function. We searched the literature in 12 electronic databases from their inception to November 2013, with full text available and language limited to English. Twenty-three studies were identified under the selection criteria. All recruited animal studies demonstrate a significant positive effect of acupuncture on cognitive impairment. Findings suggest acupuncture may improve cognitive function through modulation of signaling pathways involved in neuronal survival and function, specifically, through promoting cholinergic neural transmission, facilitating dopaminergic synaptic transmission, enhancing neurotrophin signaling, suppressing oxidative stress, attenuating apoptosis, regulating glycometabolic enzymes and reducing microglial activation. However, the quality of reviewed studies has room for improvement. Further high-quality animal studies with randomization, blinding and estimation of sample size are needed to strengthen the recognition of group differences.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 3%
Unknown 35 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 17%
Student > Doctoral Student 4 11%
Researcher 3 8%
Student > Bachelor 3 8%
Student > Postgraduate 2 6%
Other 7 19%
Unknown 11 31%
Readers by discipline Count As %
Medicine and Dentistry 8 22%
Psychology 4 11%
Nursing and Health Professions 3 8%
Agricultural and Biological Sciences 2 6%
Neuroscience 2 6%
Other 8 22%
Unknown 9 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2014.
All research outputs
#16,454,538
of 24,217,893 outputs
Outputs from Journal of Neuroimmune Pharmacology
#396
of 583 outputs
Outputs of similar age
#137,957
of 232,993 outputs
Outputs of similar age from Journal of Neuroimmune Pharmacology
#6
of 9 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 583 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 232,993 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.