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Ancient Antimicrobial Peptides Kill Antibiotic-Resistant Pathogens: Australian Mammals Provide New Options

Overview of attention for article published in PLOS ONE, August 2011
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (98th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
4 news outlets
blogs
2 blogs
twitter
9 X users
facebook
2 Facebook pages
wikipedia
1 Wikipedia page
googleplus
2 Google+ users

Citations

dimensions_citation
83 Dimensions

Readers on

mendeley
134 Mendeley
citeulike
4 CiteULike
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Title
Ancient Antimicrobial Peptides Kill Antibiotic-Resistant Pathogens: Australian Mammals Provide New Options
Published in
PLOS ONE, August 2011
DOI 10.1371/journal.pone.0024030
Pubmed ID
Authors

Jianghui Wang, Emily S. W. Wong, Jane C. Whitley, Jian Li, Jessica M. Stringer, Kirsty R. Short, Marilyn B. Renfree, Katherine Belov, Benjamin G. Cocks

Abstract

To overcome the increasing resistance of pathogens to existing antibiotics the 10×'20 Initiative declared the urgent need for a global commitment to develop 10 new antimicrobial drugs by the year 2020. Naturally occurring animal antibiotics are an obvious place to start. The recently sequenced genomes of mammals that are divergent from human and mouse, including the tammar wallaby and the platypus, provide an opportunity to discover novel antimicrobials. Marsupials and monotremes are ideal potential sources of new antimicrobials because they give birth to underdeveloped immunologically naïve young that develop outside the sterile confines of a uterus in harsh pathogen-laden environments. While their adaptive immune system develops innate immune factors produced either by the mother or by the young must play a key role in protecting the immune-compromised young. In this study we focus on the cathelicidins, a key family of antimicrobial peptide genes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 134 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Colombia 2 1%
Portugal 1 <1%
Sweden 1 <1%
Brazil 1 <1%
Spain 1 <1%
Belgium 1 <1%
Unknown 124 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 26 19%
Student > Ph. D. Student 24 18%
Student > Master 20 15%
Student > Bachelor 12 9%
Student > Postgraduate 9 7%
Other 20 15%
Unknown 23 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 65 49%
Biochemistry, Genetics and Molecular Biology 12 9%
Medicine and Dentistry 10 7%
Immunology and Microbiology 7 5%
Computer Science 2 1%
Other 13 10%
Unknown 25 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 64. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2019.
All research outputs
#631,266
of 24,374,350 outputs
Outputs from PLOS ONE
#8,682
of 210,233 outputs
Outputs of similar age
#2,370
of 127,577 outputs
Outputs of similar age from PLOS ONE
#95
of 2,536 outputs
Altmetric has tracked 24,374,350 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 210,233 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 127,577 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 2,536 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.