| Title |
Probiotic Soy Milk Consumption and Renal Function Among Type 2 Diabetic Patients with Nephropathy: a Randomized Controlled Clinical Trial
|
|---|---|
| Published in |
Probiotics and Antimicrobial Proteins, September 2017
|
| DOI | 10.1007/s12602-017-9325-3 |
| Pubmed ID | |
| Authors |
Maryam Miraghajani, Nafiseh Zaghian, Abolfazl dehkohneh, Maryam Mirlohi, Reza Ghiasvand |
| Abstract |
Diabetic nephropathy (DN) is one the most important complications of diabetes leading to end-stage renal disease. Dietary approaches have been considered to control of the kidney function deterioration among these patients. The aim of the present study was to determine the effects of fortified soy milk with Lactobacillus plantarum A7 on renal function biomarkers in type 2 DN patients. Forty-eight DN subjects were attended to this parallel randomized trial study. Participants were randomly assigned to consume a diet containing 200 mL/day probiotic soy milk in intervention group or soy milk in the control condition for 8 weeks. An inflammatory adipokine-Progranulin (PGRN), a cytokine receptor-soluble tumor necrosis factor receptor 1 (sTNFR1), and serum levels of Neutrophil gelatinase-associated lipocalin (NGAL) and cystatin C (Cys-C) as the new renal function biomarkers were measured after 8 weeks of intervention according to the standard protocol. Our analysis showed that consumption of probiotic soy milk resulted in a significant reduction in the Cys-C and PGRN levels compared with the soy milk (P = 0.01) in the final adjusted model. In addition, after adjustment for age, weight, and energy intake, a marginally significant in the NGAL level was seen between two groups (P = 0.05). However, there was no significant differences on the sTNFR1concenteration between two groups (P = 0.06). Overall, intake of probiotic soy milk may have a beneficial effect on the renal function in patients with DN. |
X Demographics
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Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 122 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 122 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 16% |
| Student > Bachelor | 12 | 10% |
| Researcher | 10 | 8% |
| Other | 5 | 4% |
| Student > Ph. D. Student | 5 | 4% |
| Other | 18 | 15% |
| Unknown | 53 | 43% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 24 | 20% |
| Agricultural and Biological Sciences | 9 | 7% |
| Immunology and Microbiology | 7 | 6% |
| Biochemistry, Genetics and Molecular Biology | 5 | 4% |
| Nursing and Health Professions | 3 | 2% |
| Other | 17 | 14% |
| Unknown | 57 | 47% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2017.
All research outputs
#14,956,396
of 23,870,022 outputs
Outputs from Probiotics and Antimicrobial Proteins
#209
of 598 outputs
Outputs of similar age
#177,946
of 318,765 outputs
Outputs of similar age from Probiotics and Antimicrobial Proteins
#9
of 19 outputs
Altmetric has tracked 23,870,022 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 598 research outputs from this source. They receive a mean Attention Score of 4.2. This one has gotten more attention than average, scoring higher than 65% of its peers.
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We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.