Title |
Interrelatedness between C-reactive protein and oxidized low-density lipoprotein
|
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Published in |
Clinical Chemistry and Laboratory Medicine, July 2014
|
DOI | 10.1515/cclm-2014-0590 |
Pubmed ID | |
Authors |
Milan M. Obradovic, Andreja Trpkovic, Vladan Bajic, Sanja Soskic, Aleksandra Jovanovic, Julijana Stanimirovic, Milos Panic, Esma R. Isenovic |
Abstract |
Abstract C-reactive protein (CRP) is a marker of inflammation. Atherosclerosis is now recognized as inflammatory disease, and it seems that CRP directly contributes to atherogenesis. Oxidation of low-density lipoprotein (LDL) molecule increases the uptake of lipid products by macrophages leading to cholesterol accumulation and subsequent foam cell formation. The elevated levels of high sensitivity CRP (hsCRP) and oxidized LDL (OxLDL) in the blood were found to be associated with cardiovascular diseases (CVD). In this review, we highlighted the evidence that CRP and OxLDL are involved in interrelated (patho) physiological pathways. The findings on association between hsCRP and OxLDL in the clinical setting will be also summarized. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Scientists | 1 | 33% |
Members of the public | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 4% |
Unknown | 22 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 5 | 22% |
Student > Ph. D. Student | 4 | 17% |
Student > Doctoral Student | 2 | 9% |
Student > Master | 2 | 9% |
Professor | 2 | 9% |
Other | 4 | 17% |
Unknown | 4 | 17% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 6 | 26% |
Immunology and Microbiology | 4 | 17% |
Biochemistry, Genetics and Molecular Biology | 2 | 9% |
Psychology | 2 | 9% |
Nursing and Health Professions | 1 | 4% |
Other | 4 | 17% |
Unknown | 4 | 17% |