| Title |
Cytokine secretion from brain macrophages infected with human immunodeficiency virus in vitro and treated with raltegravir
|
|---|---|
| Published in |
BMC Infectious Diseases, July 2014
|
| DOI | 10.1186/1471-2334-14-386 |
| Pubmed ID | |
| Authors |
Erick T Tatro, Benchawanna Soontornniyomkij, Scott L Letendre, Cristian L Achim |
| Abstract |
Integrase inhibitors are a promising class of antiretroviral drugs to treat chronic human immunodeficiency virus (HIV) infection. During HIV infection, macrophages can extravasate from the blood to the brain, while producing chemotaxic proteins and cytokines, which have detrimental effects on central nervous system cells. The main goal of this study was to understand the effects of raltegravir (RAL) on human brain macrophage production of immune-mediators when infected with HIV, but did not compare with other antiretroviral agents. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | 4% |
| Unknown | 27 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 8 | 29% |
| Student > Master | 4 | 14% |
| Student > Doctoral Student | 3 | 11% |
| Other | 2 | 7% |
| Student > Postgraduate | 2 | 7% |
| Other | 3 | 11% |
| Unknown | 6 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 4 | 14% |
| Immunology and Microbiology | 4 | 14% |
| Neuroscience | 3 | 11% |
| Medicine and Dentistry | 3 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 7% |
| Other | 5 | 18% |
| Unknown | 7 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2014.
All research outputs
#17,723,043
of 22,758,248 outputs
Outputs from BMC Infectious Diseases
#5,087
of 7,664 outputs
Outputs of similar age
#153,631
of 226,417 outputs
Outputs of similar age from BMC Infectious Diseases
#113
of 152 outputs
Altmetric has tracked 22,758,248 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,664 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
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