Restriction Endonucleases

Chapter 1 A Nomenclature for Restriction Enzymes, DNA Methyltransferases, Homing Endonucleases, and Their Genes

Chapter 2 Restriction-Modification Systems as Minimal Forms of Life

Chapter 3 Molecular Phylogenetics of Restriction Endonucleases

Chapter 4 Sliding or Hopping? How Restriction Enzymes Find Their Way on DNA

Chapter 5 The Type I and III Restriction Endonucleases: Structural Elements in Molecular Motors that Process DNA

Chapter 6 The Integration of Recognition and Cleavage: X-Ray Structures of Pre-Transition State Complex, Post-Reactive Complex, and the DNA-Free Endonuclease

Chapter 7 Structure and Function of EcoRV Endonuclease

Chapter 8 Two of A Kind: BamHI and BglII

Chapter 9 Structure and Function of the Tetrameric Restriction Enzymes

Chapter 10 Structure and Function of Type IIE Restriction Endonucleases — or: From a Plasmid That Restricts Phage Replication to A New Molecular DNA Recognition Mechanism

Chapter 11 Analysis of Type II Restriction Endonucleases that Interact with Two Recognition Sites

Chapter 12 The Role of Water in the EcoRI-DNA Binding

Chapter 13 Role of Metal Ions in Promoting DNA Binding and Cleavage by Restriction Endonucleases

Chapter 14 Restriction Endonucleases: Structure of the Conserved Catalytic Core and the Role of Metal Ions in DNA Cleavage

Chapter 15 Protein Engineering of Restriction Enzymes

Chapter 16 Engineering and Applications of Chimeric Nucleases