Title |
Management of Metastatic Spinal Cord Compression
|
---|---|
Published in |
Southern Medical Journal, September 2017
|
DOI | 10.14423/smj.0000000000000700 |
Pubmed ID | |
Authors |
Quaovi Sodji, Joseph Kaminski, Christopher Willey, Nathan Kim, Waleed Mourad, John Vender, Byron Dasher |
Abstract |
Cancer metastasis is a key event in tumor progression associated not only with mortality but also significant morbidity. Metastatic disease can promote end-organ dysfunction and even failure through mass effect compression of various vital organs including the spinal cord. In such cases, prompt medical attention is needed to restore neurological function, relieve pain, and prevent permanent damage. The three therapeutic approaches to managing metastatic spinal cord compression include corticosteroids, surgery, and radiation therapy. Although each may improve patients' symptoms, their combination has yielded the best outcome. In cancer patients with clinical suspicion of spinal cord compression, dexamethasone should be initiated followed by surgical decompression, when possible, and radiation. The latter becomes the preferred treatment in patients with inoperable disease. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 43 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 6 | 14% |
Other | 5 | 12% |
Researcher | 5 | 12% |
Student > Postgraduate | 4 | 9% |
Student > Ph. D. Student | 4 | 9% |
Other | 4 | 9% |
Unknown | 15 | 35% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 19 | 44% |
Nursing and Health Professions | 3 | 7% |
Sports and Recreations | 2 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Unknown | 18 | 42% |