Title |
Role of zinc in regulation of arterial blood pressure and in the etiopathogenesis of arterial hypertension
|
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Published in |
Biological Trace Element Research, June 2007
|
DOI | 10.1007/bf02698082 |
Pubmed ID | |
Authors |
Sławomir Tubek |
Abstract |
Increased gastrointestinal absorption and urinary excretion of zinc has been confirmed in experimental and clinical studies on primary arterial hypertension as a result from changes of intracellular and extracellular zinc content. In arterial hypertension, the levels of zinc in serum, lymphocyte, and bone decrease while increasing in heart, erythrocytes, kidney, liver, suprarenal glands and spleen. These changes result in the loss of zinc homeostasis that leads to various degrees of deficiency, not entirely compensated by nutritional factors or increased absorption in the gastrointestinal tract. Loss of zinc homeostasis can be both cause and effect of high blood pressure. In the present review, the role of zinc metabolism changes and its mechanisms in arterial hypertension are discussed. |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 41 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 5 | 12% |
Student > Bachelor | 5 | 12% |
Professor | 4 | 10% |
Student > Doctoral Student | 4 | 10% |
Student > Ph. D. Student | 3 | 7% |
Other | 8 | 20% |
Unknown | 12 | 29% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 7 | 17% |
Chemistry | 4 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 5% |
Agricultural and Biological Sciences | 2 | 5% |
Other | 3 | 7% |
Unknown | 12 | 29% |