You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Targeting EMT in cancer: opportunities for pharmacological intervention
|
|---|---|
| Published in |
Trends in Pharmacological Sciences, July 2014
|
| DOI | 10.1016/j.tips.2014.06.006 |
| Pubmed ID | |
| Authors |
Felicity M. Davis, Teneale A. Stewart, Erik W. Thompson, Gregory R. Monteith |
| Abstract |
The spread of cancer cells to distant organs represents a major clinical challenge in the treatment of cancer. Epithelial-mesenchymal transition (EMT) has emerged as a key regulator of metastasis in some cancers by conferring an invasive phenotype. As well as facilitating metastasis, EMT is thought to generate cancer stem cells and contribute to therapy resistance. Therefore, the EMT pathway is of great therapeutic interest in the treatment of cancer and could be targeted either to prevent tumor dissemination in patients at high risk of developing metastatic lesions or to eradicate existing metastatic cancer cells in patients with more advanced disease. In this review, we discuss approaches for the design of EMT-based therapies in cancer, summarize evidence for some of the proposed EMT targets, and review the potential advantages and pitfalls of each approach. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 25% |
| United States | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 261 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| Brazil | 1 | <1% |
| Unknown | 257 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 67 | 26% |
| Researcher | 40 | 15% |
| Student > Master | 31 | 12% |
| Student > Bachelor | 29 | 11% |
| Student > Doctoral Student | 13 | 5% |
| Other | 43 | 16% |
| Unknown | 38 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 77 | 30% |
| Biochemistry, Genetics and Molecular Biology | 69 | 26% |
| Medicine and Dentistry | 33 | 13% |
| Engineering | 11 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 10 | 4% |
| Other | 16 | 6% |
| Unknown | 45 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 July 2022.
All research outputs
#4,159,040
of 25,374,917 outputs
Outputs from Trends in Pharmacological Sciences
#585
of 2,406 outputs
Outputs of similar age
#38,660
of 241,800 outputs
Outputs of similar age from Trends in Pharmacological Sciences
#5
of 19 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,406 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 241,800 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.