| Title |
Molecular Heterogeneity of Triple-Negative Breast Cancer
|
|---|---|
| Published in |
Current Breast Cancer Reports, June 2014
|
| DOI | 10.1007/s12609-014-0152-1 |
| Pubmed ID | |
| Authors |
Vandana G. Abramson, Ingrid A. Mayer |
| Abstract |
Triple-negative breast cancers (TNBCs) are known to be an aggressive group of breast cancers with higher rates of relapse stage for stage compared to ER/PR positive and HER2 positive breast cancers despite optimal loco-regional and systemic therapies. To date, not a single targeted therapy has been approved for the treatment of TNBC, and cytotoxic chemotherapy remains the standard systemic treatment. Recently, gene expression analyses identified six distinct TNBC subtypes, each displaying a unique biology. In this review we will discuss current and upcoming therapeutic strategies exploring novel approaches to targeted treatment of these TNBC subtypes. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 54 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 24% |
| Student > Bachelor | 9 | 17% |
| Researcher | 9 | 17% |
| Student > Ph. D. Student | 7 | 13% |
| Professor > Associate Professor | 4 | 7% |
| Other | 7 | 13% |
| Unknown | 5 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 26% |
| Biochemistry, Genetics and Molecular Biology | 13 | 24% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 11% |
| Medicine and Dentistry | 6 | 11% |
| Computer Science | 2 | 4% |
| Other | 5 | 9% |
| Unknown | 8 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2014.
All research outputs
#17,723,634
of 22,758,963 outputs
Outputs from Current Breast Cancer Reports
#102
of 159 outputs
Outputs of similar age
#155,726
of 228,024 outputs
Outputs of similar age from Current Breast Cancer Reports
#8
of 10 outputs
Altmetric has tracked 22,758,963 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 159 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,024 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.