Title |
Current approaches to micro-RNA analysis and target gene prediction
|
---|---|
Published in |
Journal of Applied Genetics, September 2011
|
DOI | 10.1007/s13353-011-0060-2 |
Pubmed ID | |
Authors |
Tenzin W. Lhakhang, M. Ahmad Chaudhry |
Abstract |
It is becoming increasingly evident that micro-RNAs (miRNA) play a significant role in regulating the cellular machinery. These ∼22-nt non-coding RNAs function as negative regulators of gene expression. Since their discovery, considerable information has been obtained on miRNA biology and the mechanism of their action. Guidelines have been established for miRNA nomenclature and databases have been built to house all miRNA from many species. A number of methodologies are available for miRNA analysis. There is a lot of interest in developing bioinformatics approaches to predict miRNA target genes. This article will bring together the information on our current knowledge of miRNA biology, the approaches for miRNA analysis, and computational strategies to gain insight in miRNA functional roles. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Australia | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Poland | 2 | 3% |
India | 1 | 2% |
Netherlands | 1 | 2% |
United States | 1 | 2% |
United Kingdom | 1 | 2% |
Unknown | 57 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 19 | 30% |
Researcher | 15 | 24% |
Student > Master | 7 | 11% |
Professor > Associate Professor | 3 | 5% |
Student > Bachelor | 3 | 5% |
Other | 7 | 11% |
Unknown | 9 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 21 | 33% |
Biochemistry, Genetics and Molecular Biology | 13 | 21% |
Medicine and Dentistry | 10 | 16% |
Computer Science | 6 | 10% |
Nursing and Health Professions | 1 | 2% |
Other | 3 | 5% |
Unknown | 9 | 14% |