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Activation of ATP-Sensitive Potassium Channels Antagonize Nociceptive Behavior and Hyperexcitability of DRG Neurons from Rats

Overview of attention for article published in Molecular Pain, January 2011
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Title
Activation of ATP-Sensitive Potassium Channels Antagonize Nociceptive Behavior and Hyperexcitability of DRG Neurons from Rats
Published in
Molecular Pain, January 2011
DOI 10.1186/1744-8069-7-35
Pubmed ID
Authors

Xiaona Du, Chao Wang, Hailin Zhang

Abstract

Nociceptive responses to noxious stimuli are initiated at peripheral nociceptor terminals. Ion channels play a vital role in pain signal initiation and conduction. Activation of KATP channels has been implicated in mediating the analgesic effects of agents such as morphine. However, systematic studies regarding the effects of KATP activators on nociception and neuronal excitability are scarce.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 24%
Researcher 4 12%
Student > Bachelor 3 9%
Professor 3 9%
Other 3 9%
Other 8 24%
Unknown 4 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 24%
Medicine and Dentistry 7 21%
Neuroscience 6 18%
Biochemistry, Genetics and Molecular Biology 2 6%
Physics and Astronomy 1 3%
Other 3 9%
Unknown 6 18%