Title |
Neues in der Pathophysiologie der atopischen Dermatitis
|
---|---|
Published in |
Die Dermatologie, July 2006
|
DOI | 10.1007/s00105-006-1175-y |
Pubmed ID | |
Authors |
T. Hinz, A. Staudacher, T. Bieber |
Abstract |
The incidence of atopic dermatitis (AD) is noticeably increasing in industrialized countries. New insights into the pathogenesis of this disease are mirrored by a changed terminology suggested by the World Allergy Organization: a distinction between a so-called atopic and non-atopic dermatitis. The pathogenesis of the AD, which this article concentrates on, is highly complex. Genetic and environmental factors play a pivotal role in triggering AD. The complex pattern of cytokines and chemokines, reflecting a deviated immune response in AD patients, is a focus of research, as are the involvement of various cells and the epidermal barrier. Research concerning T cells with regulatory features as well as IgE-mediated autoreactivity will soon give insight into the defective tolerance of atopic patients and might possibly lead to new concepts in the management of the disease. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 7 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 1 | 14% |
Student > Doctoral Student | 1 | 14% |
Student > Ph. D. Student | 1 | 14% |
Student > Master | 1 | 14% |
Researcher | 1 | 14% |
Other | 0 | 0% |
Unknown | 2 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 3 | 43% |
Agricultural and Biological Sciences | 1 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 14% |
Unknown | 2 | 29% |