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Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway

Overview of attention for article published in Cellular Oncology, July 2014
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Title
Translational suppression of HIF-1α by miconazole through the mTOR signaling pathway
Published in
Cellular Oncology, July 2014
DOI 10.1007/s13402-014-0182-8
Pubmed ID
Authors

Jee-Young Park, Hui-Jung Jung, Incheol Seo, Bijay Kumar Jha, Seong-Il Suh, Min-Ho Suh, Won-Ki Baek

Abstract

Miconazole is an imidazole antifungal agent that has amply been used in the treatment of superficial mycosis. Preliminary data indicate that miconazole may also induce anticancer effects. As yet, however, little is known about the therapeutic efficacy of miconazole on cancer and the putative mechanism(s) involved. Here, we show that miconazole suppresses hypoxia inducible factor-1α (HIF-1α) protein translation in different cancer-derived cells.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 2 22%
Other 1 11%
Lecturer > Senior Lecturer 1 11%
Student > Master 1 11%
Researcher 1 11%
Other 0 0%
Unknown 3 33%
Readers by discipline Count As %
Medicine and Dentistry 2 22%
Pharmacology, Toxicology and Pharmaceutical Science 1 11%
Psychology 1 11%
Agricultural and Biological Sciences 1 11%
Unknown 4 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 July 2014.
All research outputs
#21,498,958
of 23,999,200 outputs
Outputs from Cellular Oncology
#316
of 426 outputs
Outputs of similar age
#198,721
of 232,626 outputs
Outputs of similar age from Cellular Oncology
#9
of 11 outputs
Altmetric has tracked 23,999,200 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 426 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 232,626 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.