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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Post-exposure efficacy of Oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model
|
|---|---|
| Published in |
Antiviral Research, January 2014
|
| DOI | 10.1016/j.antiviral.2014.01.012 |
| Pubmed ID | |
| Authors |
Sophie J. Smither, Lin S. Eastaugh, Jackie A. Steward, Michelle Nelson, Robert P. Lenk, Mark S. Lever |
| Abstract |
Filoviruses cause disease with high case fatality rates and are considered biological threat agents. Licensed post-exposure therapies that can be administered by the oral route are desired for safe and rapid distribution and uptake in the event of exposure or outbreaks. Favipiravir or T-705 has broad antiviral activity and has already undergone phase II and is undergoing phase III clinical trials for influenza. Here we report the first use of T-705 against Ebola virus. T-705 gave 100% protection against aerosol Ebola virus E718 infection; protection was shown in immune-deficient mice after 14 days of twice-daily dosing. T-705 was also shown to inhibit Ebola virus infection in cell culture. T-705 is likely to be licensed for use against influenza in the near future and could also be used with a new indication for filovirus infection. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 2 | 33% |
| Unknown | 4 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 219 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 1% |
| Japan | 3 | 1% |
| Colombia | 2 | <1% |
| Indonesia | 2 | <1% |
| Spain | 2 | <1% |
| Italy | 1 | <1% |
| United Kingdom | 1 | <1% |
| Mexico | 1 | <1% |
| Germany | 1 | <1% |
| Other | 2 | <1% |
| Unknown | 201 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 40 | 18% |
| Student > Ph. D. Student | 36 | 16% |
| Student > Bachelor | 30 | 14% |
| Student > Master | 29 | 13% |
| Other | 13 | 6% |
| Other | 40 | 18% |
| Unknown | 31 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 53 | 24% |
| Medicine and Dentistry | 39 | 18% |
| Chemistry | 16 | 7% |
| Immunology and Microbiology | 12 | 5% |
| Biochemistry, Genetics and Molecular Biology | 11 | 5% |
| Other | 46 | 21% |
| Unknown | 42 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 32. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2023.
All research outputs
#1,251,665
of 25,373,627 outputs
Outputs from Antiviral Research
#134
of 2,835 outputs
Outputs of similar age
#13,792
of 320,960 outputs
Outputs of similar age from Antiviral Research
#3
of 28 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,835 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.5. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,960 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.