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Transmembrane Protein 55B Is a Novel Regulator of Cellular Cholesterol Metabolism

Overview of attention for article published in Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire), July 2014
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4 X users

Citations

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19 Dimensions

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32 Mendeley
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Title
Transmembrane Protein 55B Is a Novel Regulator of Cellular Cholesterol Metabolism
Published in
Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire), July 2014
DOI 10.1161/atvbaha.113.302806
Pubmed ID
Authors

Marisa W Medina, Frederick Bauzon, Devesh Naidoo, Elizabeth Theusch, Kristen Stevens, Jessica Schilde, Christian Schubert, Lara M Mangravite, Lawrence L Rudel, Ryan E Temel, Heiko Runz, Ronald M Krauss

Abstract

Interindividual variation in pathways affecting cellular cholesterol metabolism can influence levels of plasma cholesterol, a well-established risk factor for cardiovascular disease. Inherent variation among immortalized lymphoblastoid cell lines from different donors can be leveraged to discover novel genes that modulate cellular cholesterol metabolism. The objective of this study was to identify novel genes that regulate cholesterol metabolism by testing for evidence of correlated gene expression with cellular levels of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) mRNA, a marker for cellular cholesterol homeostasis, in a large panel of lymphoblastoid cell lines.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 22%
Researcher 6 19%
Student > Bachelor 5 16%
Other 3 9%
Lecturer 2 6%
Other 4 13%
Unknown 5 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 31%
Agricultural and Biological Sciences 7 22%
Medicine and Dentistry 6 19%
Psychology 1 3%
Sports and Recreations 1 3%
Other 1 3%
Unknown 6 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 April 2020.
All research outputs
#14,913,921
of 25,371,288 outputs
Outputs from Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire)
#4,323
of 6,068 outputs
Outputs of similar age
#111,878
of 227,499 outputs
Outputs of similar age from Arteriosclerosis, Thrombosis, and Vascular Biology (Highwire)
#21
of 41 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,068 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,499 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.