| Title |
Cancer stem cell detection and isolation
|
|---|---|
| Published in |
Medical Oncology, July 2014
|
| DOI | 10.1007/s12032-014-0069-6 |
| Pubmed ID | |
| Authors |
Meysam Moghbeli, Faezeh Moghbeli, Mohammad Mahdi Forghanifard, Mohammad Reza Abbaszadegan |
| Abstract |
Only 10 % of cancer-related deaths result from primary tumors; most are caused by metastatic tumors. It is believed that the metastatic power of tumor cells is attributed to features of a stem cell-like subpopulation of tumor cells known as cancer stem cells (CSCs). Cancer stem cells are resistant to chemotherapeutic treatments and can induce dormancy in tumor cells for long periods. Detection, isolation, and characterization of CSCs in solid tumors are hallmarks of cancer-targeted therapies in recent years. There are inevitable similarities between normal and cancer stem cells; therefore, finding specific methods or markers to differentiate them is critical to cancer therapies. Considering CSCs involvement in tumor relapse and chemotherapeutic resistance, identification of such cells in tumors is imperative for effective targeted therapy. The present review introduces practical and specific protocols used to isolate CSCs from solid tumors from colon, esophagus, liver, breast, brain, and cervix. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Taiwan | 1 | 33% |
| Germany | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 118 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 1 | <1% |
| Switzerland | 1 | <1% |
| Italy | 1 | <1% |
| Iran, Islamic Republic of | 1 | <1% |
| United States | 1 | <1% |
| Luxembourg | 1 | <1% |
| Unknown | 112 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 22% |
| Student > Master | 18 | 15% |
| Student > Bachelor | 16 | 14% |
| Researcher | 16 | 14% |
| Student > Doctoral Student | 7 | 6% |
| Other | 14 | 12% |
| Unknown | 21 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 30 | 25% |
| Biochemistry, Genetics and Molecular Biology | 24 | 20% |
| Medicine and Dentistry | 18 | 15% |
| Engineering | 5 | 4% |
| Chemistry | 4 | 3% |
| Other | 14 | 12% |
| Unknown | 23 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 November 2014.
All research outputs
#13,917,593
of 22,759,618 outputs
Outputs from Medical Oncology
#529
of 1,286 outputs
Outputs of similar age
#115,396
of 229,429 outputs
Outputs of similar age from Medical Oncology
#8
of 34 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,286 research outputs from this source. They receive a mean Attention Score of 3.0. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,429 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.