Title |
Experimental transmission of atypical scrapie to sheep
|
---|---|
Published in |
BMC Veterinary Research, August 2007
|
DOI | 10.1186/1746-6148-3-20 |
Pubmed ID | |
Authors |
Marion M Simmons, Timm Konold, Hugh A Simmons, Yvonne I Spencer, Richard Lockey, John Spiropoulos, Sharon Everitt, Derek Clifford |
Abstract |
Active surveillance for transmissible spongiform encephalopathies in small ruminants has been an EU regulatory requirement since 2002. A number of European countries have subsequently reported cases of atypical scrapie, similar to previously published cases from Norway, which have pathological and molecular features distinct from classical scrapie. Most cases have occurred singly in flocks, associated with genotypes considered to be more resistant to classical disease. Experimental transmissibility of such isolates has been reported in certain ovinised transgenic mice, but has not previously been reported in the natural host. Information on the transmissibility of this agent is vital to ensuring that disease control measures are effective and proportionate. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | 6% |
Unknown | 17 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 33% |
Student > Doctoral Student | 3 | 17% |
Student > Ph. D. Student | 3 | 17% |
Professor | 1 | 6% |
Librarian | 1 | 6% |
Other | 2 | 11% |
Unknown | 2 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 39% |
Biochemistry, Genetics and Molecular Biology | 3 | 17% |
Veterinary Science and Veterinary Medicine | 1 | 6% |
Immunology and Microbiology | 1 | 6% |
Medicine and Dentistry | 1 | 6% |
Other | 2 | 11% |
Unknown | 3 | 17% |