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Bafetinib inhibits PAR2‐TRPV4 coupling

Overview of attention for article published in British Journal of Pharmacology, July 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (53rd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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4 X users
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1 Facebook page

Citations

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42 Dimensions

Readers on

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38 Mendeley
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Title
Bafetinib inhibits PAR2‐TRPV4 coupling
Published in
British Journal of Pharmacology, July 2014
DOI 10.1111/bph.12750
Pubmed ID
Authors

M S Grace, T Lieu, B Darby, F C Abogadie, N Veldhuis, N W Bunnett, P McIntyre

Abstract

Protease-activated receptor 2 (PAR2) is expressed on nociceptive neurons, and can sensitize transient receptor potential (TRP) ion channels to amplify neurogenic inflammation and pain. The mechanisms by which this occurs are not fully understood. PAR2 causes receptor-operated activation of TRPV4 channels and TRPV4 null mice have attenuated PAR2-stimulated neurogenic inflammation and mechanical hyperalgesia. Here we investigate the intracellular signalling mechanisms underlying PAR2-induced TRPV4 channel activation and pain.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 34%
Student > Master 5 13%
Researcher 5 13%
Student > Bachelor 3 8%
Student > Doctoral Student 2 5%
Other 3 8%
Unknown 7 18%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 26%
Pharmacology, Toxicology and Pharmaceutical Science 5 13%
Agricultural and Biological Sciences 4 11%
Neuroscience 4 11%
Medicine and Dentistry 3 8%
Other 5 13%
Unknown 7 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 August 2014.
All research outputs
#14,021,565
of 24,549,201 outputs
Outputs from British Journal of Pharmacology
#5,651
of 7,594 outputs
Outputs of similar age
#107,873
of 233,794 outputs
Outputs of similar age from British Journal of Pharmacology
#62
of 113 outputs
Altmetric has tracked 24,549,201 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,594 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 233,794 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 113 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.