| Title |
Human African trypanosomiasis in endemic populations and travellers
|
|---|---|
| Published in |
European Journal of Clinical Microbiology & Infectious Diseases, September 2011
|
| DOI | 10.1007/s10096-011-1403-y |
| Pubmed ID | |
| Authors |
J. A. Blum, A. L. Neumayr, C. F. Hatz |
| Abstract |
Human African trypanosomiasis (HAT) or sleeping sickness is caused by the protozoan parasites Trypanosoma brucei (T.b.) gambiense (West African form) and T.b. rhodesiense (East African form) that are transmitted by the bite of the tsetse fly, Glossina spp.. Whereas most patients in endemic populations are infected with T.b. gambiense, most tourists are infected with T.b. rhodesiense. In endemic populations, T.b. gambiense HAT is characterized by chronic and intermittent fever, headache, pruritus, and lymphadenopathy in the first stage and by sleep disturbances and neuro-psychiatric disorders in the second stage. Recent descriptions of the clinical presentation of T.b. rhodesiense in endemic populations show a high variability in different foci. The symptomatology of travellers is markedly different from the usual textbook descriptions of African HAT patients. The onset of both infections is almost invariably an acute and febrile disease. Diagnosis and treatment are difficult and rely mostly on old methods and drugs. However, new molecular diagnostic technologies are under development. A promising new drug combination is currently evaluated in a phase 3 b study and further new drugs are under evaluation. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 25% |
| Switzerland | 1 | 25% |
| United States | 1 | 25% |
| Egypt | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 2 | 50% |
| Scientists | 1 | 25% |
| Members of the public | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 74 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 28% |
| Student > Postgraduate | 12 | 16% |
| Student > Bachelor | 7 | 9% |
| Researcher | 7 | 9% |
| Student > Master | 6 | 8% |
| Other | 14 | 19% |
| Unknown | 7 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 22 | 30% |
| Biochemistry, Genetics and Molecular Biology | 15 | 20% |
| Medicine and Dentistry | 14 | 19% |
| Nursing and Health Professions | 5 | 7% |
| Immunology and Microbiology | 2 | 3% |
| Other | 8 | 11% |
| Unknown | 8 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 July 2012.
All research outputs
#13,353,865
of 22,651,245 outputs
Outputs from European Journal of Clinical Microbiology & Infectious Diseases
#1,593
of 2,766 outputs
Outputs of similar age
#79,707
of 125,706 outputs
Outputs of similar age from European Journal of Clinical Microbiology & Infectious Diseases
#19
of 31 outputs
Altmetric has tracked 22,651,245 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,766 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one is in the 41st percentile – i.e., 41% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 125,706 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.