Title |
Genomic Encyclopedia of Bacteria and Archaea: Sequencing a Myriad of Type Strains
|
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Published in |
PLoS Biology, August 2014
|
DOI | 10.1371/journal.pbio.1001920 |
Pubmed ID | |
Authors |
Nikos C Kyrpides, Philip Hugenholtz, Jonathan A Eisen, Tanja Woyke, Markus Göker, Charles T Parker, Rudolf Amann, Brian J Beck, Patrick S G Chain, Jongsik Chun, Rita R Colwell, Antoine Danchin, Peter Dawyndt, Tom Dedeurwaerdere, Edward F DeLong, John C Detter, Paul De Vos, Timothy J Donohue, Xiu-Zhu Dong, Dusko S Ehrlich, Claire Fraser, Richard Gibbs, Jack Gilbert, Paul Gilna, Frank Oliver Glöckner, Janet K Jansson, Jay D Keasling, Rob Knight, David Labeda, Alla Lapidus, Jung-Sook Lee, Wen-Jun Li, Juncai Ma, Victor Markowitz, Edward R B Moore, Mark Morrison, Folker Meyer, Karen E Nelson, Moriya Ohkuma, Christos A Ouzounis, Norman Pace, Julian Parkhill, Nan Qin, Ramon Rossello-Mora, Johannes Sikorski, David Smith, Mitch Sogin, Rick Stevens, Uli Stingl, Ken-Ichiro Suzuki, Dorothea Taylor, Jim M Tiedje, Brian Tindall, Michael Wagner, George Weinstock, Jean Weissenbach, Owen White, Jun Wang, Lixin Zhang, Yu-Guang Zhou, Dawn Field, William B Whitman, George M Garrity, Hans-Peter Klenk |
Abstract |
Microbes hold the key to life. They hold the secrets to our past (as the descendants of the earliest forms of life) and the prospects for our future (as we mine their genes for solutions to some of the planet's most pressing problems, from global warming to antibiotic resistance). However, the piecemeal approach that has defined efforts to study microbial genetic diversity for over 20 years and in over 30,000 genome projects risks squandering that promise. These efforts have covered less than 20% of the diversity of the cultured archaeal and bacterial species, which represent just 15% of the overall known prokaryotic diversity. Here we call for the funding of a systematic effort to produce a comprehensive genomic catalog of all cultured Bacteria and Archaea by sequencing, where available, the type strain of each species with a validly published name (currently∼11,000). This effort will provide an unprecedented level of coverage of our planet's genetic diversity, allow for the large-scale discovery of novel genes and functions, and lead to an improved understanding of microbial evolution and function in the environment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 26 | 27% |
United Kingdom | 7 | 7% |
France | 6 | 6% |
Canada | 4 | 4% |
Germany | 4 | 4% |
India | 4 | 4% |
Australia | 2 | 2% |
Japan | 2 | 2% |
Norway | 2 | 2% |
Other | 12 | 12% |
Unknown | 29 | 30% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 48 | 49% |
Members of the public | 43 | 44% |
Science communicators (journalists, bloggers, editors) | 5 | 5% |
Practitioners (doctors, other healthcare professionals) | 2 | 2% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 16 | 5% |
Germany | 8 | 2% |
Sweden | 2 | <1% |
France | 2 | <1% |
Switzerland | 1 | <1% |
Portugal | 1 | <1% |
Canada | 1 | <1% |
Saudi Arabia | 1 | <1% |
Taiwan | 1 | <1% |
Other | 5 | 1% |
Unknown | 306 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 85 | 25% |
Student > Ph. D. Student | 79 | 23% |
Professor | 32 | 9% |
Student > Master | 29 | 8% |
Student > Bachelor | 29 | 8% |
Other | 59 | 17% |
Unknown | 31 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 161 | 47% |
Biochemistry, Genetics and Molecular Biology | 55 | 16% |
Environmental Science | 22 | 6% |
Immunology and Microbiology | 18 | 5% |
Medicine and Dentistry | 8 | 2% |
Other | 41 | 12% |
Unknown | 39 | 11% |