Title |
Metabolite signatures of exercise training in human skeletal muscle relate to mitochondrial remodelling and cardiometabolic fitness
|
---|---|
Published in |
Diabetologia, August 2014
|
DOI | 10.1007/s00125-014-3343-4 |
Pubmed ID | |
Authors |
Kim M. Huffman, Timothy R. Koves, Monica J. Hubal, Hiba Abouassi, Nina Beri, Lori A. Bateman, Robert D. Stevens, Olga R. Ilkayeva, Eric P. Hoffman, Deborah M. Muoio, William E. Kraus |
Abstract |
Targeted metabolomic and transcriptomic approaches were used to evaluate the relationship between skeletal muscle metabolite signatures, gene expression profiles and clinical outcomes in response to various exercise training interventions. We hypothesised that changes in mitochondrial metabolic intermediates would predict improvements in clinical risk factors, thereby offering novel insights into potential mechanisms. |
X Demographics
The data shown below were collected from the profiles of 20 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 20% |
United Kingdom | 4 | 20% |
Germany | 1 | 5% |
Canada | 1 | 5% |
Unknown | 10 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 13 | 65% |
Scientists | 6 | 30% |
Unknown | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 226 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 1% |
United States | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 221 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 37 | 16% |
Researcher | 28 | 12% |
Student > Master | 25 | 11% |
Student > Bachelor | 20 | 9% |
Professor | 15 | 7% |
Other | 50 | 22% |
Unknown | 51 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 33 | 15% |
Biochemistry, Genetics and Molecular Biology | 32 | 14% |
Sports and Recreations | 29 | 13% |
Agricultural and Biological Sciences | 19 | 8% |
Nursing and Health Professions | 7 | 3% |
Other | 35 | 15% |
Unknown | 71 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2015.
All research outputs
#2,760,126
of 22,759,618 outputs
Outputs from Diabetologia
#1,370
of 5,034 outputs
Outputs of similar age
#29,107
of 230,115 outputs
Outputs of similar age from Diabetologia
#14
of 51 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,034 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one has gotten more attention than average, scoring higher than 72% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,115 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.