| Title |
Carotenoids and breast cancer risk: a meta-analysis and meta-regression
|
|---|---|
| Published in |
Breast Cancer Research and Treatment, September 2011
|
| DOI | 10.1007/s10549-011-1723-8 |
| Pubmed ID | |
| Authors |
Fulan Hu, Baina Wang Yi, Wencui Zhang, Jing Liang, Chunqing Lin, Dandan Li, Fan Wang, Da Pang, Yashuang Zhao |
| Abstract |
The purpose of this article is to comprehensively summarize the associations between carotenoids and breast cancer and quantitatively estimate their dose-response relationships. We searched PubMed, Embase, and Cochrane databases (from January 1982 to 1 May 2011) and the references of the relevant articles in English with sufficient information to estimate relative risk or odds ratio and the 95% confidence intervals, and comparable categories of carotenoids. Two reviewers independently extracted data using a standardized form; with any discrepancy adjudicated by the third reviewer. 33 studies met the inclusion criteria. Comparing the highest with the lowest intake: dietary α-carotene intake significantly reduced the breast cancer risk by 9.0% (pooled RR = 0.91; 95% CI: 0.85-0.98; P = 0.01), dietary β-carotene intake reduced the risk by 6.0% (pooled RR = 0.94; 95% CI: 0.88-1.00; P = 0.05); total β-carotene intake reduced the risk by 5.0% (pooled RR = 0.95; 95% CI: 0.90-1.01; P = 0.08) when data from cohort studies were pooled. Significant dose-response relationships were observed in both the higher intake of dietary and total β-carotene with reduced breast cancer risk when data from cohort studies (P (trend) < 0.01, P (trend) = 0.03) and case-control studies (P (trend) < 0.01, P (trend) < 0.01) were pooled, respectively. Dietary α-carotene intake could reduce the breast cancer risk. The relationships between dietary and total β-carotene intake and breast cancer need to be confirmed. No significant association between dietary intake of β-cryptoxanthin, lutein/+zeaxanthin, and lycopene and breast cancer was observed. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 3% |
| France | 1 | 2% |
| Egypt | 1 | 2% |
| Unknown | 61 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 18% |
| Student > Master | 9 | 14% |
| Student > Bachelor | 9 | 14% |
| Student > Postgraduate | 7 | 11% |
| Researcher | 5 | 8% |
| Other | 11 | 17% |
| Unknown | 12 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 20% |
| Agricultural and Biological Sciences | 8 | 12% |
| Nursing and Health Professions | 7 | 11% |
| Biochemistry, Genetics and Molecular Biology | 5 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Other | 7 | 11% |
| Unknown | 22 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 67. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2023.
All research outputs
#613,789
of 24,669,628 outputs
Outputs from Breast Cancer Research and Treatment
#55
of 4,889 outputs
Outputs of similar age
#2,304
of 129,470 outputs
Outputs of similar age from Breast Cancer Research and Treatment
#1
of 50 outputs
Altmetric has tracked 24,669,628 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,889 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.