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Disruption of vascular homeostasis in patients with Kawasaki disease: Involvement of vascular endothelial growth factor and angiopoietins

Overview of attention for article published in Arthritis & Rheumatism, December 2011
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Title
Disruption of vascular homeostasis in patients with Kawasaki disease: Involvement of vascular endothelial growth factor and angiopoietins
Published in
Arthritis & Rheumatism, December 2011
DOI 10.1002/art.33316
Pubmed ID
Authors

Willemijn B. Breunis, Sonia Davila, Chisato Shimizu, Toshiaki Oharaseki, Kei Takahashi, Michel van Houdt, Chiea Chuen Khor, Victoria J. Wright, Michael Levin, Jane C. Burns, David Burgner, Martin L. Hibberd, Taco W. Kuijpers, International Kawasaki Disease Genetics Consortium

Abstract

In Kawasaki disease (KD), a pediatric vasculitis of medium-sized arteries, the coronary arteries are most commonly affected. Angiopoietins and vascular endothelial growth factor (VEGF) play an important role in maintaining vascular homeostasis. Recently, we identified ANGPT1 and VEGFA as susceptibility loci for KD. This study was undertaken to fine-map these associations and to gain further insight into their role in this vasculitis of unknown etiology to further the search for improved diagnostic and therapeutic options.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Finland 1 2%
United States 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 21%
Student > Master 8 19%
Other 5 12%
Student > Ph. D. Student 4 10%
Professor > Associate Professor 3 7%
Other 9 21%
Unknown 4 10%
Readers by discipline Count As %
Medicine and Dentistry 20 48%
Agricultural and Biological Sciences 5 12%
Biochemistry, Genetics and Molecular Biology 2 5%
Nursing and Health Professions 2 5%
Computer Science 1 2%
Other 2 5%
Unknown 10 24%