↓ Skip to main content

Application of redox proteomics to skeletal muscle aging and exercise.

Overview of attention for article published in Biochemical Society Transactions, August 2014
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (62nd percentile)

Mentioned by

twitter
4 X users

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
33 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Application of redox proteomics to skeletal muscle aging and exercise.
Published in
Biochemical Society Transactions, August 2014
DOI 10.1042/bst20140085
Pubmed ID
Authors

Brian McDonagh, Giorgos K Sakellariou, Malcolm J Jackson

Abstract

Skeletal muscle represents a physiologically relevant model for the application of redox proteomic techniques to dissect its response to exercise and aging. Contracting skeletal muscles generate ROS (reactive oxygen species) and RNS (reactive nitrogen species) necessary for the regulation of many proteins involved in excitation-contraction coupling. The magnitude and species of ROS/RNS generated by contracting muscles will have downstream effects on specific protein targets and cellular redox signalling. Redox modifications on specific proteins are essential for the adaptive response to exercise and skeletal muscle can develop a dysregulated redox response during aging. In the present article, we discuss how redox proteomics can be applied to identify and quantify the reversible modifications on susceptible cysteine residues within those redox-sensitive proteins, and the integration of oxidative and non-oxidative protein modifications in relation to the functional proteome.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Greece 1 3%
Unknown 32 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 27%
Researcher 6 18%
Student > Doctoral Student 3 9%
Professor > Associate Professor 3 9%
Lecturer 2 6%
Other 8 24%
Unknown 2 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 36%
Biochemistry, Genetics and Molecular Biology 9 27%
Medicine and Dentistry 5 15%
Sports and Recreations 3 9%
Environmental Science 1 3%
Other 1 3%
Unknown 2 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2017.
All research outputs
#13,410,980
of 22,759,618 outputs
Outputs from Biochemical Society Transactions
#2,516
of 3,329 outputs
Outputs of similar age
#109,876
of 230,877 outputs
Outputs of similar age from Biochemical Society Transactions
#20
of 53 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,329 research outputs from this source. They receive a mean Attention Score of 4.6. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,877 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.