Title |
Comparative genomics highlights the unique biology of Methanomassiliicoccales, a Thermoplasmatales-related seventh order of methanogenic archaea that encodes pyrrolysine
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Published in |
BMC Genomics, August 2014
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DOI | 10.1186/1471-2164-15-679 |
Pubmed ID | |
Authors |
Guillaume Borrel, Nicolas Parisot, Hugh MB Harris, Eric Peyretaillade, Nadia Gaci, William Tottey, Olivier Bardot, Kasie Raymann, Simonetta Gribaldo, Pierre Peyret, Paul W O’Toole, Jean-François Brugère |
Abstract |
A seventh order of methanogens, the Methanomassiliicoccales, has been identified in diverse anaerobic environments including the gastrointestinal tracts (GIT) of humans and other animals and may contribute significantly to methane emission and global warming. Methanomassiliicoccales are phylogenetically distant from all other orders of methanogens and belong to a large evolutionary branch composed by lineages of non-methanogenic archaea such as Thermoplasmatales, the Deep Hydrothermal Vent Euryarchaeota-2 (DHVE-2, Aciduliprofundum boonei) and the Marine Group-II (MG-II). To better understand this new order and its relationship to other archaea, we manually curated and extensively compared the genome sequences of three Methanomassiliicoccales representatives derived from human GIT microbiota, "Candidatus Methanomethylophilus alvus", "Candidatus Methanomassiliicoccus intestinalis" and Methanomassiliicoccus luminyensis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 25% |
United States | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 50% |
Scientists | 2 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | <1% |
Australia | 1 | <1% |
Unknown | 212 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 52 | 24% |
Researcher | 36 | 17% |
Student > Master | 32 | 15% |
Student > Bachelor | 14 | 7% |
Student > Postgraduate | 9 | 4% |
Other | 30 | 14% |
Unknown | 41 | 19% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 62 | 29% |
Biochemistry, Genetics and Molecular Biology | 46 | 21% |
Environmental Science | 25 | 12% |
Immunology and Microbiology | 10 | 5% |
Earth and Planetary Sciences | 5 | 2% |
Other | 18 | 8% |
Unknown | 48 | 22% |