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A microdevice for the creation of patent, three-dimensional endothelial cell-based microcirculatory networks

Overview of attention for article published in Biomicrofluidics, August 2011
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

Mentioned by

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2 X users
patent
1 patent

Citations

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21 Dimensions

Readers on

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23 Mendeley
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Title
A microdevice for the creation of patent, three-dimensional endothelial cell-based microcirculatory networks
Published in
Biomicrofluidics, August 2011
DOI 10.1063/1.3609264
Pubmed ID
Authors

Lien T. Chau, Barbara E. Rolfe, Justin J. Cooper-White

Abstract

Microvascular network formation is a significant and challenging goal in the engineering of large three-dimensional artificial tissue structures. We show here the development of a fully patent, 3D endothelial cell (microvascular) microfluidic network that has a single inlet and outlet, created in only 28 h in a microdevice involving fluid flow equivalent to natural vasculature. Our microdevice features a tailored "multi-rung ladder" network, a stylized mimic of an arterial-to-venous pedicle, designed to also allow for systematic and reproducible cell seeding. Immunofluorescence staining revealed a highly contiguous endothelial monolayer (human umbilical vein endothelial cells) throughout the whole network after 24 h of continuous perfusion. This network persisted for up to 72 h of culture, providing a useful template from which the effects of surface chemistry, fluid flow, and environmental conditions on the development of artificial vascular networks ex vivo may be rapidly and robustly evaluated.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 43%
Researcher 5 22%
Student > Master 3 13%
Student > Doctoral Student 2 9%
Student > Bachelor 1 4%
Other 1 4%
Unknown 1 4%
Readers by discipline Count As %
Engineering 7 30%
Biochemistry, Genetics and Molecular Biology 3 13%
Computer Science 3 13%
Agricultural and Biological Sciences 2 9%
Business, Management and Accounting 1 4%
Other 2 9%
Unknown 5 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2015.
All research outputs
#6,734,743
of 24,195,945 outputs
Outputs from Biomicrofluidics
#168
of 821 outputs
Outputs of similar age
#32,159
of 109,192 outputs
Outputs of similar age from Biomicrofluidics
#5
of 23 outputs
Altmetric has tracked 24,195,945 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 821 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 109,192 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.