| Title |
Septic cardiomyopathy
|
|---|---|
| Published in |
Annals of Intensive Care, April 2011
|
| DOI | 10.1186/2110-5820-1-6 |
| Pubmed ID | |
| Authors |
Antoine Vieillard-Baron |
| Abstract |
Depression of left ventricular (LV) intrinsic contractility is constant in patients with septic shock. Because most parameters of cardiac function are strongly dependent on afterload, especially in this context, the cardiac performance evaluated at the bedside reflects intrinsic contractility, but also the degree of vasoplegia. Recent advances in echocardiography have allowed better characterization of septic cardiomyopathy. It is always reversible providing the patient's recovery. Unlike classic cardiomyopathy, it is not associated with high filling pressures, for two reasons: improvement in LV compliance and associated right ventricular dysfunction. Although, it is unclear to which extent it affects prognosis, a hyperkinetic state is indicative of a profound and persistent vasoplegia associated with a high mortality rate. Preliminary data suggest that the hemodynamic response to a dobutamine challenge has a prognostic value, but large studies are required to establish whether inotropic drugs should be used to treat this septic cardiac dysfunction. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Kuwait | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 288 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 2 | <1% |
| Turkey | 1 | <1% |
| Germany | 1 | <1% |
| Bulgaria | 1 | <1% |
| Italy | 1 | <1% |
| Brazil | 1 | <1% |
| United Kingdom | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 279 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 36 | 13% |
| Researcher | 35 | 12% |
| Other | 34 | 12% |
| Student > Ph. D. Student | 25 | 9% |
| Student > Bachelor | 24 | 8% |
| Other | 90 | 31% |
| Unknown | 44 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 192 | 67% |
| Agricultural and Biological Sciences | 10 | 3% |
| Nursing and Health Professions | 7 | 2% |
| Biochemistry, Genetics and Molecular Biology | 6 | 2% |
| Veterinary Science and Veterinary Medicine | 5 | 2% |
| Other | 21 | 7% |
| Unknown | 47 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2014.
All research outputs
#15,303,896
of 22,760,687 outputs
Outputs from Annals of Intensive Care
#818
of 1,037 outputs
Outputs of similar age
#84,600
of 108,987 outputs
Outputs of similar age from Annals of Intensive Care
#9
of 12 outputs
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