| Title |
Contralateral cerebello-thalamo-cortical pathways with prominent involvement of associative areas in humans in vivo
|
|---|---|
| Published in |
Brain Structure and Function, August 2014
|
| DOI | 10.1007/s00429-014-0861-2 |
| Pubmed ID | |
| Authors |
Fulvia Palesi, Jacques-Donald Tournier, Fernando Calamante, Nils Muhlert, Gloria Castellazzi, Declan Chard, Egidio D’Angelo, Claudia A. M. Wheeler-Kingshott |
| Abstract |
In addition to motor functions, it has become clear that in humans the cerebellum plays a significant role in cognition too, through connections with associative areas in the cerebral cortex. Classical anatomy indicates that neo-cerebellar regions are connected with the contralateral cerebral cortex through the dentate nucleus, superior cerebellar peduncle, red nucleus and ventrolateral anterior nucleus of the thalamus. The anatomical existence of these connections has been demonstrated using virus retrograde transport techniques in monkeys and rats ex vivo. In this study, using advanced diffusion MRI tractography we show that it is possible to calculate streamlines to reconstruct the pathway connecting the cerebellar cortex with contralateral cerebral cortex in humans in vivo. Corresponding areas of the cerebellar and cerebral cortex encompassed similar proportion (about 80 %) of the tract, suggesting that the majority of streamlines passing through the superior cerebellar peduncle connect the cerebellar hemispheres through the ventrolateral thalamus with contralateral associative areas. This result demonstrates that this kind of tractography is a useful tool to map connections between the cerebellum and the cerebral cortex and moreover could be used to support specific theories about the abnormal communication along these pathways in cognitive dysfunctions in pathologies ranging from dyslexia to autism. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 20% |
| Unknown | 4 | 80% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 80% |
| Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 242 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 3 | 1% |
| United States | 2 | <1% |
| Austria | 1 | <1% |
| Germany | 1 | <1% |
| India | 1 | <1% |
| Italy | 1 | <1% |
| Unknown | 233 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 51 | 21% |
| Researcher | 41 | 17% |
| Student > Master | 25 | 10% |
| Student > Bachelor | 19 | 8% |
| Other | 14 | 6% |
| Other | 44 | 18% |
| Unknown | 48 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 67 | 28% |
| Medicine and Dentistry | 29 | 12% |
| Psychology | 28 | 12% |
| Engineering | 18 | 7% |
| Agricultural and Biological Sciences | 11 | 5% |
| Other | 28 | 12% |
| Unknown | 61 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2018.
All research outputs
#3,191,064
of 24,217,893 outputs
Outputs from Brain Structure and Function
#243
of 1,725 outputs
Outputs of similar age
#32,263
of 239,918 outputs
Outputs of similar age from Brain Structure and Function
#4
of 48 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,725 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 239,918 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.