Title |
The lncRNA-MYC regulatory network in cancer
|
---|---|
Published in |
Tumor Biology, August 2014
|
DOI | 10.1007/s13277-014-2511-y |
Pubmed ID | |
Authors |
Kaiyuan Deng, Xiaoqiang Guo, Hao Wang, Jiazeng Xia |
Abstract |
Long non-coding RNAs (lncRNAs) have been widely studied in recent years, and accumulating evidence identified lncRNAs as crucial regulators of various biological processes, including cell cycle progression, chromatin remodeling, gene transcription, and posttranscriptional processing. In addition, the fact that lncRNAs interact with the MYC gene family in human carcinomas has been discovered. This review summarizes the latest progress on the investigation of lncRNAs and MYC, particularly focusing on the interplay between lncRNAs and MYC in cancer to reveal the significance of lncRNA-MYC network in regulating initiation, development, and metastasis of tumors. Further research and collection of clinical data would provide a better understanding of lncRNA-MYC network in cancer diagnosis and treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 2% |
Taiwan | 1 | 2% |
Unknown | 44 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 14 | 30% |
Researcher | 12 | 26% |
Student > Master | 6 | 13% |
Student > Doctoral Student | 2 | 4% |
Student > Postgraduate | 2 | 4% |
Other | 2 | 4% |
Unknown | 8 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 39% |
Biochemistry, Genetics and Molecular Biology | 12 | 26% |
Medicine and Dentistry | 5 | 11% |
Computer Science | 1 | 2% |
Neuroscience | 1 | 2% |
Other | 0 | 0% |
Unknown | 9 | 20% |