Title |
Melanoma: Diagnosis, Staging, and Treatment. Consensus group recommendations
|
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Published in |
Advances in Therapy, August 2014
|
DOI | 10.1007/s12325-014-0148-2 |
Pubmed ID | |
Authors |
Alfonso Berrocal, Luis Cabañas, Enrique Espinosa, Ricardo Fernández-de-Misa, Salvador Martín-Algarra, José Carlos Martínez-Cedres, Luis Ríos-Buceta, José Luis Rodríguez-Peralto |
Abstract |
The incidence of malignant melanoma is increasing worldwide. In Spain, its incidence is increasing faster than any other cancer type, with a 5-year survival rate of about 85%. The impact and characteristics of malignant melanoma in the Spanish population can be ascertained from the national melanoma registry of the Academia Española de Dermatología y Venereología. This review presents consensus group recommendations for the diagnosis, staging and treatment of malignant melanoma in Spain. Incidence and mortality are discussed, as well as evaluation of various prevention and treatment strategies. Prognostic factors, such as BRAF and C-KIT mutations, which are expected to become routine staging procedures over the next few years, are outlined, especially in relation to treatment options. The use of recently approved targeted agents such as ipilimumab, a cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) inhibitor, and vemurafenib, a BRAF inhibitor, in metastatic disease are also discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Ecuador | 1 | 2% |
Unknown | 44 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 13% |
Student > Bachelor | 6 | 13% |
Student > Doctoral Student | 5 | 11% |
Other | 4 | 9% |
Student > Master | 4 | 9% |
Other | 10 | 22% |
Unknown | 10 | 22% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 19 | 42% |
Biochemistry, Genetics and Molecular Biology | 3 | 7% |
Agricultural and Biological Sciences | 3 | 7% |
Immunology and Microbiology | 2 | 4% |
Nursing and Health Professions | 1 | 2% |
Other | 2 | 4% |
Unknown | 15 | 33% |