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Transforming Growth Factor-β in Cancer Therapy, Volume I

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Cover of 'Transforming Growth Factor-β in Cancer Therapy, Volume I'

Table of Contents

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    Book Overview
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    Chapter 1 Component Hardware for Transforming Growth Factor-β Signal Transduction: TGF-β Ligands, TGF-β Receptors, and Smads
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    Chapter 2 TGF-β Signaling in Homeostasis and Cancer
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    Chapter 3 TGF-β Availability: Latent TGF-β and Latent TGF-β Binding Proteins
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    Chapter 4 Biological Functions of Latent TGF-β-Binding Proteins and Activation of TGF-β
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    Chapter 5 Regulators of Smad2/3 Transcription and Phosphorylation
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    Chapter 6 Interaction of Smad4 and Embryonic Liver Fodrin-β-spectrin in Hyperplasia, Neoplasia, and Tumor Suppression
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    Chapter 7 Regulation of Smad Activity by Phosphorylation
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    Chapter 8 Nuclear Targeting of TGF-β-Activated Smads in Normal and Tumor Biology
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    Chapter 9 Ski, SnoN, and Akt as Negative Regulators of Smad Activity: Balancing Cell Death and Cell Survival
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    Chapter 10 Transforming Growth Factor-β in Cancer Therapy: Smurfs in TGF-β Signaling and Regulation of Bone Homeostasis and Cancer
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    Chapter 11 Involvement of km23 Dynein Light Chains in TGF β Signaling
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    Chapter 12 TGF-β Signaling in Fibroblastic Cells and Oncogenesis
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    Chapter 13 Mechanisms of TGF-β-Induced Apoptosis in Cancer Cells
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    Chapter 14 Mechanisms of Cell Cycle Regulation by TGF-β Disabled in Cancer
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    Chapter 15 Transforming Growth Factor-β in Cancer Therapy
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    Chapter 16 TGF-β and Smad Signaling in Transcriptome Reprogramming During EMT
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    Chapter 17 Functional Interactions Between MMPs and TGF-β in Normal and Tumor Tissue
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    Chapter 18 Cooperation Between TGF-β and Wnt Pathway Components in Regulating Mesenchymal Stem Cell Function
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    Chapter 19 Interaction of Oncogenic Ras and TGFβ1 Signaling in Cancer: Lessons From the Multistage Skin Carcinogenesis Model
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    Chapter 20 Proteomics Analysis of TGFβ Superfamily Members
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    Chapter 21 Mullerian Inhibiting Substance: A Potential Nontoxic, Naturally Occurring Therapeutic Agent for Certain Human Cancers
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    Chapter 22 Activins, Inhibins, and Bone Morphogenetic Proteins as Modulators and Biomarkers of Prostate Cancer Progression
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    Chapter 23 Bone Morphogenic Proteins and Angiogenesis in Developing Tumors
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    Chapter 24 Histone Methyltransferase and Smad Interactions in BMP Signaling
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    Chapter 25 Endoglin (CD105): A Strong Candidate for Immunologic Targeting of Tumor Neovasculature in Human Malignancies
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    Chapter 26 Activins and Inhibins in Cancer Progression
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    Chapter 27 Bone Morphogenetic Proteins/Growth Differentiation Factors and Smad Activation in Ovarian Granulosa Cells and Carcinoma
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    Chapter 28 Regulation of the Transforming Growth Factor-β Superfamily by Betaglycan
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    Chapter 29 Uterine Sensitization Associated Gene-1: A Bone Morphogenetic Protein Antagonist with a Role in Kidney
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    Chapter 30 Role of Betaig-h3 Gene in Carcinogenesis
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    Chapter 31 Activins and the Liver
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    Chapter 32 Myostatin Signaling in Normal and Tumor Cells
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    Chapter 33 Triterpenoids, Vitamin D, and TGF-β/Smad Signaling in Inflammation and Cancer
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    Chapter 34 Thrombospondin-Dependent Activation of Latent TGF-β in Fibrosis and Disease
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    Chapter 35 TGF-β in Pulmonary Fibrosis
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    Chapter 36 The Role of TGF-β in Bleomycin Induced Pulmonary Fibrosis
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    Chapter 37 Smads in the Fibrotic Response: Findings in the Smad3 Knockout Mouse
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    Chapter 38 TGF-β Signaling in Renal Fibrosis and Inflammation: Gene Therapy Using Ultrasound-Microbubble-Mediated Inducible Smad7
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    Chapter 39 Transforming Growth Factor-β Peptide Signaling in Pulmonary Development, Bronchopulmonary Dysplasia, Fibrosis, and Emphysema
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    Chapter 40 The Role of TGF-β in Radiation and Chemotherapy Induced Pulmonary Fibrosis: Inhibition of TGF-β as a Novel Therapeutic Strategy
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    Chapter 41 Negative Regulation of the TGF-β Family Signal Pathway by Inhibitory Smads and Their Involvement in Cancer and Fibrosis
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    Chapter 42 TGF-β-Related Antifibrotic Strategies in the Eye
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    Chapter 43 Transforming Growth Factor-β in Cutaneous Tissue Repair
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    Chapter 44 Topical Application of TGF-β1 Peptide Inhibitors for the Therapy of Skin Fibrosis
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    Chapter 45 Overexpressed Truncated TGF-β Type II Receptor Inhibits Fibrotic Behavior of Keloid Fibroblasts In Vitro and Experimental Scar Formation In Vivo
Overall attention for this book and its chapters
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Title
Transforming Growth Factor-β in Cancer Therapy, Volume I
Published by
Springer Science & Business Media, January 2010
DOI 10.1007/978-1-59745-292-2
ISBNs
978-1-59745-292-2, 978-1-58829-714-3
Authors

Sonia B. Jakowlew, Jakowlew, Sonia B.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 17%
Unknown 5 83%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 50%
Researcher 1 17%
Student > Master 1 17%
Unknown 1 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 67%
Pharmacology, Toxicology and Pharmaceutical Science 1 17%
Unknown 1 17%