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Connecting the dots between tau dysfunction and neurodegeneration

Overview of attention for article published in Trends in Cell Biology, August 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

Mentioned by

twitter
8 X users
patent
5 patents
facebook
2 Facebook pages

Citations

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102 Dimensions

Readers on

mendeley
242 Mendeley
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Title
Connecting the dots between tau dysfunction and neurodegeneration
Published in
Trends in Cell Biology, August 2014
DOI 10.1016/j.tcb.2014.07.005
Pubmed ID
Authors

Bess Frost, Jürgen Götz, Mel B. Feany

Abstract

Tauopathies are devastating and ultimately fatal neurodegenerative diseases, which are histopathologically defined by insoluble filamentous deposits of abnormally phosphorylated tau protein within neurons and glia. Identifying the causes of abnormal tau phosphorylation and subsequent aggregation has been the focus of much research, and is currently a major target for the development of therapeutic interventions for tauopathies, including Alzheimer's disease (AD). Much has recently been learned about the sequence of events that lead from tau dysfunction to neuronal death. This review focuses on the cascade of events that are catalyzed by pathological tau, and highlights current and potential therapeutic strategies to target this pathway.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 242 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 3 1%
United States 2 <1%
Korea, Republic of 2 <1%
Germany 1 <1%
United Kingdom 1 <1%
Chile 1 <1%
Unknown 232 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 64 26%
Researcher 44 18%
Student > Bachelor 30 12%
Student > Master 27 11%
Student > Doctoral Student 14 6%
Other 34 14%
Unknown 29 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 71 29%
Neuroscience 49 20%
Biochemistry, Genetics and Molecular Biology 41 17%
Medicine and Dentistry 20 8%
Chemistry 8 3%
Other 18 7%
Unknown 35 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 April 2024.
All research outputs
#4,614,798
of 25,503,365 outputs
Outputs from Trends in Cell Biology
#592
of 1,965 outputs
Outputs of similar age
#43,431
of 247,362 outputs
Outputs of similar age from Trends in Cell Biology
#8
of 26 outputs
Altmetric has tracked 25,503,365 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,965 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,362 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.