| Title |
Long-lasting subjective effects of LSD in normal subjects
|
|---|---|
| Published in |
Psychopharmacology, September 2017
|
| DOI | 10.1007/s00213-017-4733-3 |
| Pubmed ID | |
| Authors |
Yasmin Schmid, Matthias E. Liechti |
| Abstract |
Lysergic acid diethylamide (LSD) and other serotonergic hallucinogens can induce profound alterations of consciousness and mystical-type experiences, with reportedly long-lasting effects on subjective well-being and personality. We investigated the lasting effects of a single dose of LSD (200 μg) that was administered in a laboratory setting in 16 healthy participants. The following outcome measures were assessed before and 1 and 12 months after LSD administration: Persisting Effects Questionnaire (PEQ), Mysticism Scale (MS), Death Transcendence Scale (DTS), NEO-Five Factor Inventory (NEO-FFI), and State-Trait Anxiety Inventory (STAI). On the PEQ, positive attitudes about life and/or self, positive mood changes, altruistic/positive social effects, positive behavioral changes, and well-being/life satisfaction significantly increased at 1 and 12 months and were subjectively attributed by the subjects to the LSD experience. Five-Dimensions of Altered States of Consciousness (5D-ASC) total scores, reflecting acutely induced alterations in consciousness, and Mystical Experience Questionnaire (MEQ30) total scores correlated with changes in well-being/life satisfaction 12 months after LSD administration. No changes in negative attitudes, negative mood, antisocial/negative social effects, or negative behavior were attributed to the LSD experience. After 12 months, 10 of 14 participants rated their LSD experience as among the top 10 most meaningful experiences in their lives. Five participants rated the LSD experience among the five most spiritually meaningful experiences in their lives. On the MS and DTS, ratings of mystical experiences significantly increased 1 and 12 months after LSD administration compared with the pre-LSD screening. No relevant changes in personality measures were found. In healthy research subjects, the administration of a single dose of LSD (200 μg) in a safe setting was subjectively considered a personally meaningful experience that had long-lasting subjective positive effects. Registration identification number: NCT01878942. |
X Demographics
The data shown below were collected from the profiles of 81 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 13 | 16% |
| Spain | 5 | 6% |
| Australia | 3 | 4% |
| Canada | 2 | 2% |
| Argentina | 2 | 2% |
| United Kingdom | 2 | 2% |
| France | 2 | 2% |
| Brazil | 1 | 1% |
| Ecuador | 1 | 1% |
| Other | 6 | 7% |
| Unknown | 44 | 54% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 69 | 85% |
| Scientists | 6 | 7% |
| Practitioners (doctors, other healthcare professionals) | 4 | 5% |
| Science communicators (journalists, bloggers, editors) | 2 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 400 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 400 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 72 | 18% |
| Student > Master | 47 | 12% |
| Researcher | 41 | 10% |
| Student > Doctoral Student | 28 | 7% |
| Student > Ph. D. Student | 24 | 6% |
| Other | 54 | 14% |
| Unknown | 134 | 34% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 78 | 20% |
| Medicine and Dentistry | 60 | 15% |
| Neuroscience | 44 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 16 | 4% |
| Biochemistry, Genetics and Molecular Biology | 14 | 4% |
| Other | 49 | 12% |
| Unknown | 139 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 155. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2024.
All research outputs
#270,414
of 25,773,273 outputs
Outputs from Psychopharmacology
#73
of 5,358 outputs
Outputs of similar age
#5,421
of 310,751 outputs
Outputs of similar age from Psychopharmacology
#1
of 45 outputs
Altmetric has tracked 25,773,273 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,358 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has done particularly well, scoring higher than 98% of its peers.
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We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.