| Title |
Correlation Between Iodine Intake and Thyroid Disorders: A Cross-Sectional Study from the South of China
|
|---|---|
| Published in |
Biological Trace Element Research, August 2014
|
| DOI | 10.1007/s12011-014-0102-9 |
| Pubmed ID | |
| Authors |
Hengqiang Zhao, Yuan Tian, Zeming Liu, Xiaoyu Li, Mengyu Feng, Tao Huang |
| Abstract |
Great changes have taken place in the incidence of thyroid diseases since the implementation of universal salt iodization (USI). However, the high incidence of thyroid diseases caused by the high iodine intake has been contentious. The aim of this study was to investigate the relationship between iodine intake and thyroid diseases through the comparison of urine iodine concentration (UIC) between patients with thyroid diseases and healthy volunteers and to assess the status of iodine intake among the residents. From November 2013 to May 2014, 905 patients who underwent thyroid surgeries and 272 subjects of healthy controls were enrolled and were divided into two groups: the case group and the control group, respectively. Levels of thyroid hormones and thyroid autoantibodies in serum from blood were analyzed among all the patients. UIC and thyroid B ultrasounds were performed on each participant. The median urinary iodine (MUI) concentration was 184.5 and 169.6 μg/L for case group and control group, respectively (P = 0.003). Significant differences of the MUI were found between healthy controls and patients with Hashimoto's thyroiditis (MUI = 221.3 μg/L), nodular goiter (MUI = 193.5 μg/L), multiple nodules (MUI = 185.9 μg/L), nodule diameter ≥1 cm (MUI = 194.4 μg/L), hyperthyroidism (MUI = 258.7 μg/L), thyroid peroxidase antibody (TPOAb) (+), and thyroglobulin antibody (TGAb) (+) (MUI = 196.4 μg/L), and P values were 0.003, 0.000, 0.002, 0.000, 0.000, and 0.001, respectively. The susceptibility of the thyroid diseases among normal people was significantly associated with female sex (odds ratio (OR) = 3.3), older age (OR = 2.1), and high iodine intake (OR = 1.3). In conclusion, high iodine intake was likely to lead to the occurrence of thyroid diseases, such as Hashimoto thyroiditis, nodular goiter, and hyperthyroidism, through a long-term mechanism. USI should continue to be carried out and individual UIC detection was recommended for the disequilibrium of the iodine nutritional status among normal people. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Spain | 1 | 2% |
| Unknown | 44 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 12 | 26% |
| Student > Master | 10 | 22% |
| Student > Ph. D. Student | 5 | 11% |
| Researcher | 2 | 4% |
| Student > Doctoral Student | 2 | 4% |
| Other | 3 | 7% |
| Unknown | 12 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 28% |
| Nursing and Health Professions | 10 | 22% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Economics, Econometrics and Finance | 2 | 4% |
| Business, Management and Accounting | 1 | 2% |
| Other | 4 | 9% |
| Unknown | 13 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2023.
All research outputs
#4,029,939
of 24,766,831 outputs
Outputs from Biological Trace Element Research
#227
of 2,219 outputs
Outputs of similar age
#38,898
of 242,129 outputs
Outputs of similar age from Biological Trace Element Research
#2
of 32 outputs
Altmetric has tracked 24,766,831 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,219 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done well, scoring higher than 89% of its peers.
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