| Title |
Canonical Notch signalling is inactive in urothelial carcinoma
|
|---|---|
| Published in |
BMC Cancer, August 2014
|
| DOI | 10.1186/1471-2407-14-628 |
| Pubmed ID | |
| Authors |
Annemarie Greife, Silvia Jankowiak, Jochen Steinbring, Parvaneh Nikpour, Günter Niegisch, Michèle J Hoffmann, Wolfgang A Schulz |
| Abstract |
Notch signalling regulates cell fate in most tissues, promoting precursor cell proliferation in some, but differentiation in others. Accordingly, downregulation or overactivity variously contributes to cancer development. So far, little is known about Notch pathway activity and function in the normal urothelium and in urothelial carcinoma (UC). We have therefore investigated expression of Notch pathway components in UC tissues and cell lines and studied the function of one receptor, NOTCH1, in detail. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Taiwan | 1 | 3% |
| Unknown | 34 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 9 | 26% |
| Student > Bachelor | 7 | 20% |
| Researcher | 5 | 14% |
| Student > Master | 5 | 14% |
| Student > Postgraduate | 2 | 6% |
| Other | 3 | 9% |
| Unknown | 4 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 8 | 23% |
| Agricultural and Biological Sciences | 8 | 23% |
| Medicine and Dentistry | 8 | 23% |
| Immunology and Microbiology | 3 | 9% |
| Sports and Recreations | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 6 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 June 2021.
All research outputs
#6,941,665
of 22,761,738 outputs
Outputs from BMC Cancer
#1,834
of 8,277 outputs
Outputs of similar age
#68,550
of 236,210 outputs
Outputs of similar age from BMC Cancer
#32
of 158 outputs
Altmetric has tracked 22,761,738 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 8,277 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,210 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 158 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.